Batatasin Iii

Batatasin Iii

SCHEMBL29629601

COc1cc(O)cc(CCc2cccc(O)c2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 1.00
GABRG2 P18507 1/20 1.00
GABRB3 P28472 1/20 1.00
GABRA3 P34903 1/20 1.00
GABRA2 P47869 1/20 1.00
GABRB2 P47870 1/20 1.00
CALM1 P0DP23 6/20 0.70
PTPN1 P18031 2/20 0.65
NOS2 P35228 1/20 0.65
AKR1B1 P15121 2/20 0.62
PTGS2 P35354 1/20 0.58
POLB P06746 1/20 0.51
TAAR1 Q96RJ0 2/20 0.50
CHRM2 P08172 1/20 0.50
CHRM1 P11229 1/20 0.50
CHRM3 P20309 1/20 0.50
DRD2 P14416 1/20 0.50
DRD1 P21728 1/20 0.50
F2 P00734 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Batatasin Iii SCHEMBL11505373 1.00 GABRA1 (1.00) GABRA1GABRG2GABRB3GABRA3GABRA2
Batatasin Iii SCHEMBL29352616 1.00 GABRA1 (1.00) GABRA1GABRG2GABRB3GABRA3GABRA2
SCHEMBL20179598 0.95 GABRA1 (0.90) GABRA1GABRG2GABRB3GABRA3GABRA2
SCHEMBL30574244 0.93 GABRA1 (0.87) GABRA1GABRG2GABRB3GABRA3GABRA2
SCHEMBL27968568 0.89 GABRA1 (0.81) GABRA1GABRG2GABRB3GABRA3GABRA2
SCHEMBL11504762 0.88 GABRA1 (0.78) GABRA1GABRG2GABRB3GABRA3GABRA2
SCHEMBL27968433 0.84 GABRA1 (0.73) GABRA1GABRG2GABRB3GABRA3GABRA2
SCHEMBL16568144 0.82 CALM1 (0.86) GABRA1GABRG2GABRB3GABRA3GABRA2
SCHEMBL29862145 0.82 CALM1 (0.86) GABRA1GABRG2GABRB3GABRA3GABRA2
SCHEMBL27254011 0.82 CALM1 (1.00) GABRA1GABRG2GABRB3GABRA3GABRA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026314-A1 POLYPEPTIDES FOR USE IN THE SYNTHESIS OF BIOACTIVE PHENOLIC COMPOUNDS ROTHSTEIN STEVEN (CA) 2024-01-25 US claimed
EP-4251758-A1 POLYPEPTIDES FOR USE IN THE SYNTHESIS OF BIOACTIVE PHENOLIC COMPOUNDS Rothstein, Steven (CA) 2023-10-04 EP claimed
WO-2023150534-A1 SMALL MOLECULE PIM AND MTOR KINASE INHIBITOR AND METHODS OF USE THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2023-08-10 WO claimed
CN-114586627-B Planting method for promoting growth of cymbidium sinense and accumulation of active ingredients 中国科学院昆明植物研究所 2023-08-01 CN claimed
CN-114586627-A Planting method for promoting growth and effective component accumulation of Pleione 中国科学院昆明植物研究所 2022-06-07 CN claimed
WO-2022109736-A1 POLYPEPTIDES FOR USE IN THE SYNTHESIS OF BIOACTIVE PHENOLIC COMPOUNDS ROTHSTEIN STEVEN (CA) 2022-06-02 WO claimed
US-20250129045-A1 SMALL MOLECULE PIM AND MTOR KINASE INHIBITOR AND METHODS OF USE THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2025-04-24 US disclosed
EP-4496567-A1 USES OF BLETILLA FORMOSANA EXTRACT FOR THE TREATMENT OF DISEASES ASSOCIATED WITH DYSREGULATED ACTIVATION OF NEUTROPHILS Chang Gung University (TW) 2025-01-29 EP disclosed
US-20240269220-A1 USES OF BLETILLA FORMOSANA EXTRACT FOR THE TREATMENT OF DISEASES ASSOCIATED WITH DYSREGULATED ACTIVATION OF NEUTROPHILS CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) 2024-08-15 US disclosed
US-20240026314-A1 POLYPEPTIDES FOR USE IN THE SYNTHESIS OF BIOACTIVE PHENOLIC COMPOUNDS ROTHSTEIN STEVEN (CA) 2024-01-25 US disclosed
EP-4251758-A1 POLYPEPTIDES FOR USE IN THE SYNTHESIS OF BIOACTIVE PHENOLIC COMPOUNDS Rothstein, Steven (CA) 2023-10-04 EP disclosed
WO-2023178592-A1 USES OF BLETILLA FORMOSANA EXTRACT FOR THE TREATMENT OF DISEASES ASSOCIATED WITH DYSREGULATED ACTIVATION OF NEUTROPHILS CHANG GUNG UNIVERSITY (CN) 2023-09-28 WO disclosed
WO-2023150534-A1 SMALL MOLECULE PIM AND MTOR KINASE INHIBITOR AND METHODS OF USE THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2023-08-10 WO disclosed
CN-114586627-B Planting method for promoting growth of cymbidium sinense and accumulation of active ingredients 中国科学院昆明植物研究所 2023-08-01 CN disclosed
CN-114586627-B Planting method for promoting growth of cymbidium sinense and accumulation of active ingredients 中国科学院昆明植物研究所 2023-08-01 CN disclosed
CN-115845065-A Use of FN/FAK pathway inhibitor in preparation of medicine for improving thyroid cancer radioiodine treatment sensitivity 江苏省原子医学研究所 2023-03-28 CN disclosed
CN-114586627-A Planting method for promoting growth and effective component accumulation of Pleione 中国科学院昆明植物研究所 2022-06-07 CN disclosed
CN-114586627-A Planting method for promoting growth and effective component accumulation of Pleione 中国科学院昆明植物研究所 2022-06-07 CN disclosed
WO-2022109736-A1 POLYPEPTIDES FOR USE IN THE SYNTHESIS OF BIOACTIVE PHENOLIC COMPOUNDS ROTHSTEIN STEVEN (CA) 2022-06-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129045-A1 SMALL MOLECULE PIM AND MTOR KINASE INHIBITOR AND METHODS OF USE THEREOF PIM3, PIM1, PIM2 GABRA1 3988/4885GABRG2 3678/4885GABRB3 2631/4885
US-20240026314-A1 POLYPEPTIDES FOR USE IN THE SYNTHESIS OF BIOACTIVE PHENOLIC COMPOUNDS COMT, PNMT, GNMT GABRA1 4540/4885GABRG2 4454/4885GABRB3 4123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.