Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 4/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.37 |
| ▸ | FYN | P06241 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20894366 | 1.00 | HCAR3 (0.50) | HCAR3DGAT1ALDH1A1KDM4EUSP30 | |
| SCHEMBL2601997 | 0.92 | DGAT1 (0.46) | HCAR3DGAT1ALDH1A1KDM4EUSP30 | |
| SCHEMBL25066062 | 0.83 | DGAT1 (0.46) | HCAR3DGAT1USP30LPLLIPG | |
| SCHEMBL182973 | 0.83 | DGAT1 (0.46) | HCAR3DGAT1ALDH1A1KDM4EUSP30 | |
| SCHEMBL22674352 | 0.83 | DGAT1 (0.43) | DGAT1USP30LPLLIPGCA1 | |
| SCHEMBL19996746 | 0.83 | DGAT1 (0.43) | DGAT1USP30LPLLIPGCA1 | |
| SCHEMBL1842384 | 0.83 | DGAT1 (0.41) | HCAR3DGAT1ALDH1A1KDM4EUSP30 | |
| SCHEMBL25698622 | 0.81 | LRRK2 (0.43) | HCAR3DGAT1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL2432651 | 0.81 | LPL (0.50) | HCAR3DGAT1LPLLIPGCA1 | |
| SCHEMBL31262570 | 0.81 | CYP2C19 (0.47) | DGAT1USP30LPLLIPGMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563094-B | (hetero) aryl-substituted piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-03-18 | — | — | CN | disclosed |