Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.59 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CMA1 | P23946 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632475 | 1.00 | TAAR1 (1.00) | TAAR1SLC6A4CALM1SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL857029 | 0.98 | TAAR1 (0.96) | TAAR1SLC6A4CALM1SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL29836913 | 0.98 | TAAR1 (0.96) | TAAR1SLC6A4CALM1SLC6A2SLC6A3 | |
| Methane SCHEMBL11744005 | 0.98 | TAAR1 (0.96) | TAAR1SLC6A4CALM1SLC6A2SLC6A3 | |
| Hypochlorous Acid SCHEMBL7493535 | 0.94 | TAAR1 (0.89) | TAAR1SLC6A4CALM1SLC6A2SLC6A3 | |
| SCHEMBL29694229 | 0.89 | TAAR1 (0.79) | TAAR1SLC6A4CALM1SLC6A2SLC6A3 | |
| SCHEMBL1813526 | 0.89 | TAAR1 (0.79) | TAAR1SLC6A4CALM1SLC6A2SLC6A3 | |
| SCHEMBL1253622 | 0.88 | TAAR1 (0.79) | TAAR1SLC6A4CALM1SLC6A2SLC6A3 | |
| SCHEMBL108087 | 0.87 | TAAR1 (0.77) | TAAR1SLC6A4CALM1SLC6A2SLC6A3 | |
| SCHEMBL30928249 | 0.87 | TAAR1 (0.77) | TAAR1SLC6A4CALM1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093427-B | Medicine for treating Alzheimer disease and related diseases causing cognitive disorder | 哈尔滨医科大学 | 2023-03-24 | — | — | CN | claimed |
| CN-115093427-A | Medicine for treating Alzheimer disease and related diseases causing cognitive disorder | 哈尔滨医科大学 | 2022-09-23 | — | — | CN | claimed |
| US-20260053792-A1 | POLYSUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS, METHOD FOR PREPARING SAME, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2026-02-26 | — | — | US | disclosed |
| US-12441683-B2 | 7-methyl indole analogs and dosage forms containing the same | Kuleon, LLC (US) | 2025-10-14 | — | — | US | disclosed |
| US-20250282722-A1 | 7-METHYL INDOLE ANALOGS AND DOSAGE FORMS CONTAINING THE SAME | KULEON LLC (US) | 2025-09-11 | — | — | US | disclosed |
| EP-4563575-A1 | POLYSUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS, METHOD FOR PREPARING SAME, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2025-06-04 | — | — | EP | disclosed |
| US-20250049791-A1 | Synthesis of MEK7 Inhibitors and methods of Use Thereof | NORTHWESTERN UNIVERSITY | 2025-02-13 | — | — | US | disclosed |
| EP-4452986-A1 | SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME | Kuleon LLC (US) | 2024-10-30 | — | — | EP | disclosed |
| CN-114685473-B | 5-Alkyl-2-pyrazole-oxazolidine-4-ketone derivative and application thereof | 杭州百新生物医药科技有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-116270628-B | Pharmaceutical composition for preventing and treating Alzheimer disease and related diseases causing cognitive dysfunction | 哈尔滨医科大学 | 2024-08-23 | — | — | CN | disclosed |
| CN-118221633-A | TRPV1/URAT1 dual inhibitor, preparation method and application thereof | 郑州大学第一附属医院 | 2024-06-21 | — | — | CN | disclosed |
| CN-115093427-B | Medicine for treating Alzheimer disease and related diseases causing cognitive disorder | 哈尔滨医科大学 | 2023-03-24 | — | — | CN | disclosed |
| WO-2023023298-A1 | HALLUCINOGENIC AND NON-HALLUCINOGENIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | PSILOSTERICS, LLC (US) | 2023-02-23 | — | — | WO | disclosed |
| CN-115093427-A | Medicine for treating Alzheimer disease and related diseases causing cognitive disorder | 哈尔滨医科大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-114716331-A | Preparation method of dopamine hydrochloride | 福安药业集团宁波天衡制药有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114685473-A | 5-alkyl-2-pyrazole-oxazolidine-4-ketone derivative and application thereof | 杭州百新生物医药科技有限公司 | 2022-07-01 | — | — | CN | disclosed |
| WO-2022135601-A1 | 5-ALKYL-2-PYRAZOLE-OXAZOLIDINE-4-KETONE DERIVATIVE AND USE THEREOF | 杭州百新生物医药科技有限公司 | 2022-06-30 | — | — | WO | disclosed |
| CN-114634509-A | Full continuous flow preparation method of (-) -tetrahydroberberine alkaloid | 复旦大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-113735847-B | Synthetic preparation method of berberine hydrochloride | 四川大学 | 2022-06-07 | — | — | CN | disclosed |
| WO-2022115798-A2 | COMPOSITIONS AND METHODS FOR TREATING MIGRAINE | WESANA HEALTH INC. (US) | 2022-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250282722-A1 | 7-METHYL INDOLE ANALOGS AND DOSAGE FORMS CONTAINING THE SAME | HTR7, HTR2C, HTR1A | TAAR1 36/4885SLC6A4 21/4885CALM1 619/4885 |
| US-20250049791-A1 | Synthesis of MEK7 Inhibitors and methods of Use Thereof | MAPK7, MAP3K7, NRAS | TAAR1 4335/4885SLC6A4 4547/4885CALM1 3236/4885 |
| US-12441683-B2 | 7-methyl indole analogs and dosage forms containing the same | HTR7, HTR2C, HTR1A | TAAR1 36/4885SLC6A4 21/4885CALM1 619/4885 |
| US-20260053792-A1 | POLYSUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS, METHOD FOR PREPARING SAME, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | TFEB, SNCA, PARK7 | TAAR1 3918/4885SLC6A4 1723/4885CALM1 2392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.