SCHEMBL29633971

SCHEMBL29633971

CN(C(=O)OCC1c2ccccc2-c2ccccc21)C(Cc1ccc(Cl)cc1)C(=O)OC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 1/20 0.39
FABP7 O15540 2/20 0.37
FABP5 Q01469 2/20 0.37
KMT2A Q03164 2/20 0.35
NPY5R Q15761 1/20 0.35
ADAMTS5 Q9UNA0 1/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ITGB3 P05106 1/20 0.34
ITGA2B P08514 1/20 0.34
CYP3A4 P08684 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
NFKB1 P19838 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29633698 0.92 FABP5 (0.39) FABP7FABP5KMT2AITGB3ITGA2B
SCHEMBL29633925 0.91 KMT2A (0.34) FABP7FABP5KMT2AITGB3ITGA2B
SCHEMBL29633679 0.91 KMT2A (0.35) FABP7FABP5KMT2AITGB3ITGA2B
SCHEMBL29633720 0.91 PPARG (0.36) ADORA1FABP7FABP5KMT2AITGB3
SCHEMBL22454863 0.91 KMT2A (0.35) FABP7FABP5KMT2AITGB3ITGA2B
SCHEMBL29633779 0.90 ADORA1 (0.36) ADORA1FABP7FABP5KMT2ACYP3A4
SCHEMBL29633980 0.90 FABP5 (0.36) FABP7FABP5KMT2AMEN1MAPT
SCHEMBL29633897 0.89 CTSL (0.39) FABP7FABP5KMT2AMAPTNPSR1
SCHEMBL29633748 0.89 FABP5 (0.37) FABP5ITGB3ITGA2B
SCHEMBL18384380 0.88 ADORA1 (0.36) ADORA1FABP7FABP5KMT2ANPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI PHARMACEUTICAL CO LTD (JP) 2024-11-14 US disclosed
US-12071396-B2 Method for preparing aromatic amino acid derivative CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-08-27 US disclosed
US-20220144762-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE DDC, AADAT, TYR ADORA1 2955/4885FABP7 1148/4885FABP5 608/4885
US-20220144762-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE DDC, AADAT, TYR ADORA1 2955/4885FABP7 1148/4885FABP5 608/4885
US-12071396-B2 Method for preparing aromatic amino acid derivative DDC, AADAT, TYR ADORA1 2955/4885FABP7 1148/4885FABP5 608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.