SCHEMBL29633908

SCHEMBL29633908

O=C(O)CCCc1ccc(C(F)(F)F)cc1F

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.49
RXRA P19793 3/20 0.48
NR1H2 P55055 3/20 0.48
CYSLTR2 Q9NS75 1/20 0.48
CYSLTR1 Q9Y271 1/20 0.48
FFAR1 O14842 5/20 0.48
IDO1 P14902 1/20 0.47
MGLL Q99685 1/20 0.46
NR1H3 Q13133 1/20 0.46
FFAR4 Q5NUL3 3/20 0.46
PPARG P37231 4/20 0.45
PPARA Q07869 4/20 0.45
PTGDR2 Q9Y5Y4 1/20 0.43
PPARD Q03181 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12835379 1.00 DAO (0.49) DAORXRANR1H2CYSLTR2CYSLTR1
SCHEMBL584750 0.92 FFAR1 (0.54) DAOFFAR1IDO1FFAR4PTGDR2
SCHEMBL29009780 0.89 MGLL (0.47) RXRANR1H2CYSLTR2CYSLTR1FFAR1
SCHEMBL26679370 0.83 RXRA (0.50) RXRANR1H2CYSLTR2CYSLTR1FFAR1
SCHEMBL24264919 0.82 PPARG (0.47) DAORXRANR1H2FFAR1IDO1
SCHEMBL29406104 0.82 PPARG (0.47) DAORXRANR1H2FFAR1IDO1
SCHEMBL584278 0.81 IDO1 (0.51) DAOFFAR1IDO1FFAR4
SCHEMBL512428 0.81 IDO1 (0.51) DAORXRAFFAR1IDO1PTGDR2
SCHEMBL30530542 0.81 IDO1 (0.51) DAORXRAFFAR1IDO1PTGDR2
SCHEMBL11524595 0.81 MGLL (0.47) RXRANR1H2CYSLTR2CYSLTR1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209433-B Small molecule albumin binding agents 俄勒冈健康科学大学 2025-05-23 CN disclosed
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI PHARMACEUTICAL CO LTD (JP) 2024-11-14 US disclosed
US-12071396-B2 Method for preparing aromatic amino acid derivative CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-08-27 US disclosed
CN-116209433-A Small molecule albumin binding agents 俄勒冈健康科学大学 2023-06-02 CN disclosed
US-20220144762-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE DDC, AADAT, TYR DAO 7/4885RXRA 1430/4885NR1H2 3874/4885
US-20220144762-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE DDC, AADAT, TYR DAO 7/4885RXRA 1430/4885NR1H2 3874/4885
US-12071396-B2 Method for preparing aromatic amino acid derivative DDC, AADAT, TYR DAO 7/4885RXRA 1430/4885NR1H2 3874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.