SCHEMBL29634267

SCHEMBL29634267

Nc1ncnc2nc(SCc3ccccc3Cl)[nH]c12

nearest known ligand 0.74

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.74
SMN1; SMN2 Q16637 2/20 0.74
HPGD P15428 1/20 0.74
LMNA P02545 3/20 0.69
ALDH1A1 P00352 2/20 0.60
NPSR1 Q6W5P4 1/20 0.60
TSHR P16473 1/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
KDM4E B2RXH2 1/20 0.53
ERBB2 P04626 1/20 0.52
HSP90AA1 P07900 1/20 0.52
HSP90AB1 P08238 1/20 0.52
NUDT1 P36639 1/20 0.51
APEX1 P27695 1/20 0.51
CDC7 O00311 1/20 0.51
DBF4 Q9UBU7 1/20 0.51
MAPT P10636 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21788558 0.84 KMT2A (0.55) HTTSMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL5132693 0.73 LMNA (0.74) HTTSMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL3250370 0.71 LMNA (0.71) HTTSMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL17574490 0.70 LMNA (0.59) HTTSMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL1859610 0.69 ALDH1A1 (0.64) HTTSMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL12604487 0.69 NPC1 (0.73) HTTSMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL2372185 0.69 PI4KA (0.61) HTTSMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL17060218 0.69 NUDT1 (1.00) HTTSMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL1861839 0.69 ERBB2 (1.00) HTTSMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL29805612 0.68 CDC7 (1.00) HTTHPGDLMNAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118726352-A Promoter element and application thereof in biosynthesis of 3-hydroxy propionic acid 山东大学 2024-10-01 CN claimed
CN-118726352-A Promoter element and application thereof in biosynthesis of 3-hydroxy propionic acid 山东大学 2024-10-01 CN disclosed
CN-111880837-B Business process engine system supporting dynamic expansion and visual configuration 上海伯俊软件科技有限公司 2024-02-20 CN disclosed
CN-114981415-B Systems and methods for enhanced immunotherapy 杭州启函生物科技有限公司 2023-12-01 CN disclosed
US-20230338528-A1 SYSTEMS AND METHODS FOR ENHANCED IMMUNOTHERAPIES HANGZHOU QIHAN BIOTECHNOLOGY CO. LTD. (CN) 2023-10-26 US disclosed
EP-4240830-A1 SYSTEMS AND METHODS FOR ENHANCED IMMUNOTHERAPIES Hangzhou Qihan Biotechnology Co., Ltd. (CN) 2023-09-13 EP disclosed
WO-2023078287-A1 SYSTEMS AND METHODS FOR ENHANCED IMMUNOTHERAPIES HANGZHOU QIHAN BIOTECHNOLOGY CO., LTD. (CN) 2023-05-11 WO disclosed
US-20220281998-A1 BIFIDOBACTERIUM SPP. EXPRESSING AND SECRETING DIABODY-TYPE BSAB AZUSAPHARMA SCIENCES, INC. 2022-09-08 US disclosed
CN-114981415-A Systems and methods for enhanced immunotherapy 杭州启函生物科技有限公司 2022-08-30 CN disclosed
WO-2022095902-A1 SYSTEMS AND METHODS FOR ENHANCED IMMUNOTHERAPIES HANGZHOU QIHAN BIOTECHNOLOGY CO., LTD. (CN) 2022-05-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220281998-A1 BIFIDOBACTERIUM SPP. EXPRESSING AND SECRETING DIABODY-TYPE BSAB CD2, CD22, CD4 HTT 3588/4885SMN1; SMN2 2619/4885HPGD 4697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.