Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29634651 | 0.94 | L3MBTL1 (0.35) | L3MBTL1ACVR1CYP2D6HTR6ALDH1A1 | |
| SCHEMBL30051724 | 0.85 | L3MBTL1 (0.36) | L3MBTL1ACVR1CYP2D6HTR6ALDH1A1 | |
| SCHEMBL28830396 | 0.85 | L3MBTL1 (0.36) | L3MBTL1ACVR1CYP2D6HTR6ALDH1A1 | |
| SCHEMBL28830386 | 0.84 | L3MBTL1 (0.38) | L3MBTL1CYP2D6HTR6ALDH1A1CYP3A4 | |
| SCHEMBL30053626 | 0.84 | L3MBTL1 (0.38) | L3MBTL1CYP2D6HTR6ALDH1A1CYP3A4 | |
| SCHEMBL23119942 | 0.83 | L3MBTL1 (0.39) | L3MBTL1CYP2D6HTR6ALDH1A1CYP3A4 | |
| SCHEMBL29634559 | 0.83 | LMNA (0.35) | L3MBTL1ACVR1CYP2D6HTR6ALDH1A1 | |
| SCHEMBL23119940 | 0.82 | L3MBTL1 (0.36) | L3MBTL1CYP2D6HTR6ALDH1A1CYP3A4 | |
| SCHEMBL28830509 | 0.82 | L3MBTL1 (0.35) | L3MBTL1ACVR1CYP2D6HTR6ALDH1A1 | |
| SCHEMBL28830431 | 0.82 | L3MBTL1 (0.35) | L3MBTL1ACVR1CYP2D6HTR6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483514-B | Cyano-substituted cyclic hydrazine derivative and application thereof | 启元生物(杭州)有限公司 | 2022-06-14 | — | — | CN | disclosed |