SCHEMBL29634902

SCHEMBL29634902

Cc1ccc(C)c(S(=O)(=O)C=CC#N)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.60
MAPT P10636 6/20 0.60
KMT2A Q03164 5/20 0.60
TDP1 Q9NUW8 4/20 0.60
HPGD P15428 4/20 0.60
MEN1 O00255 3/20 0.60
NPC1 O15118 2/20 0.60
NFKB1 P19838 2/20 0.60
RAB9A P51151 2/20 0.60
TP53 P04637 2/20 0.60
CYP1A2 P05177 2/20 0.60
CYP3A4 P08684 2/20 0.60
CYP2D6 P10635 2/20 0.60
CYP2C9 P11712 2/20 0.60
MAPK1 P28482 2/20 0.60
CYP2C19 P33261 2/20 0.60
HSD17B10 Q99714 2/20 0.60
S100A4 P26447 1/20 0.60
MTOR P42345 1/20 0.60
NFKB2 Q00653 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20774482 0.87 ALDH1A1 (0.60) ALDH1A1MAPTKMT2ATDP1HPGD
SCHEMBL20774483 0.87 ALDH1A1 (0.60) ALDH1A1MAPTKMT2ATDP1HPGD
SCHEMBL28938489 0.79 ALDH1A1 (0.54) ALDH1A1MAPTKMT2ATDP1HPGD
SCHEMBL1120137 0.79 ALDH1A1 (0.54) ALDH1A1MAPTKMT2ATDP1HPGD
SCHEMBL161628 0.75 ALDH1A1 (1.00) ALDH1A1MAPTKMT2ATDP1HPGD
SCHEMBL20774334 0.75 ALDH1A1 (1.00) ALDH1A1MAPTKMT2ATDP1HPGD
SCHEMBL161627 0.75 ALDH1A1 (1.00) ALDH1A1MAPTKMT2ATDP1HPGD
SCHEMBL20774386 0.75 ALDH1A1 (0.67) ALDH1A1MAPTKMT2ATDP1HPGD
SCHEMBL20774385 0.75 ALDH1A1 (0.67) ALDH1A1MAPTKMT2ATDP1HPGD
SCHEMBL29634877 0.75 ALDH1A1 (0.67) ALDH1A1MAPTKMT2ATDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662200-A1 METHOD FOR PREPARING ARYLVINYLSULPHONES Kemira OYJ (FI) 2025-12-17 EP disclosed
WO-2024199939-A1 METHOD FOR PREPARING ARYLVINYLSULPHONES KEMIRA OYJ (FI) 2024-10-03 WO disclosed
EP-4214190-A1 METHOD FOR PREPARING ARYLVINYLSULPHONES Kemira OYJ (FI) 2023-07-26 EP disclosed
WO-2022096682-A1 METHOD FOR PREPARING ARYLVINYLSULPHONES KEMIRA OYJ (FI) 2022-05-12 WO disclosed