Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29635286 | 0.77 | HTT (0.41) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL28796630 | 0.76 | HTT (0.45) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL29635285 | 0.75 | HTT (0.42) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL29140074 | 0.75 | KMT2A (0.48) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL29635290 | 0.75 | MAPT (0.44) | MEN1KMT2AKDM4EMAPTHTT | |
| SCHEMBL29635289 | 0.72 | MAPT (0.50) | KMT2AKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL28796566 | 0.72 | KMT2A (0.43) | MEN1KMT2AMAPTHTT | |
| SCHEMBL9937249 | 0.72 | MAPT (0.53) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL29635288 | 0.71 | MAPT (0.46) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL18227081 | 0.68 | MAPT (0.53) | MEN1KMT2AKDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114671868-B | Polysubstituted indolizine compound containing pyridone and preparation method and application thereof | 浙大城市学院 | 2023-03-31 | — | — | CN | claimed |
| CN-114671868-A | Polysubstituted indolizine compound containing pyridone and preparation method and application thereof | 浙大城市学院 | 2022-06-28 | — | — | CN | claimed |
| CN-114671868-B | Polysubstituted indolizine compound containing pyridone and preparation method and application thereof | 浙大城市学院 | 2023-03-31 | — | — | CN | disclosed |
| CN-114671868-A | Polysubstituted indolizine compound containing pyridone and preparation method and application thereof | 浙大城市学院 | 2022-06-28 | — | — | CN | disclosed |