SCHEMBL29635316

SCHEMBL29635316

Brc1ccc(-c2ccccc2)c(Br)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
MAPK1 P28482 3/20 0.58
PTPRC P08575 1/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.43
BACE1 P56817 1/20 0.42
ALOX5 P09917 1/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
CYP19A1 P11511 1/20 0.41
ALOX15 P16050 1/20 0.41
CYP2A6 P11509 1/20 0.41
AKR1C3 P42330 1/20 0.40
AKR1C2 P52895 1/20 0.40
AKR1C1 Q04828 1/20 0.40
DCLK1 O15075 1/20 0.40
PRKD3 O94806 1/20 0.40
MAP4K4 O95819 1/20 0.40
CHEK2 O96017 1/20 0.40
CSF1R P07333 1/20 0.40
FER P16591 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4174406 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1PTPRCPTGDR2BACE1
SCHEMBL10479111 0.85 ALOX15 (0.44) ALDH1A1MAPK1PTPRCALOX15CYP2A6
SCHEMBL29789063 0.84 ALDH1A1 (0.44) ALDH1A1MAPK1ALOX15NPC1TP53
SCHEMBL364027 0.83 MAPK1 (0.52) ALDH1A1MAPK1PTPRCPTGDR2BACE1
Water SCHEMBL22361233 0.83 ALOX15 (0.42) ALDH1A1MAPK1PTPRCALOX15CYP2A6
SCHEMBL19190198 0.83 PTPRC (0.56) ALDH1A1MAPK1PTPRCPTGDR2BACE1
SCHEMBL30006434 0.83 MAPK1 (0.52) ALDH1A1MAPK1PTPRCPTGDR2BACE1
Water SCHEMBL28671726 0.82 ALDH1A1 (0.43) ALDH1A1MAPK1ALOX15NPC1TP53
SCHEMBL24542622 0.81 ALDH1A1 (0.58) ALDH1A1MAPK1BACE1ALOX5CRHBP
SCHEMBL2715170 0.81 ALDH1A1 (0.58) ALDH1A1MAPK1BACE1ALOX5CRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4103474-B1 METHOD FOR OPERATING A PASSENGER BOARDING BRIDGE OF AN AIRPORT TK AIRPORT SOLUTIONS S A (ES) 2024-09-18 EP disclosed
US-20230081313-A1 METHOD FOR OPERATING A PASSENGER BOARDING BRIDGE OF AN AIRPORT TK HOME SOLUTIONS GMBH (DE) 2023-03-16 US disclosed
EP-4103474-A1 METHOD FOR OPERATING A PASSENGER BOARDING BRIDGE OF AN AIRPORT TK Airport Solutions, S.A. (ES) 2022-12-21 EP disclosed
CN-115210143-A Method for operating a passenger bridge at an airport TK机场解决方案股份公司 2022-10-18 CN disclosed
CN-110317140-B Compound with arylamine and bis-dimethyl fluorene as cores and application thereof 江苏三月科技股份有限公司 2022-05-13 CN disclosed