SCHEMBL4174406

SCHEMBL4174406

Brc1ccc(-c2ccccc2)c(Br)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
MAPK1 P28482 3/20 0.58
PTPRC P08575 1/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.43
BACE1 P56817 1/20 0.42
ALOX5 P09917 1/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
CYP19A1 P11511 1/20 0.41
ALOX15 P16050 1/20 0.41
CYP2A6 P11509 1/20 0.41
AKR1C3 P42330 1/20 0.40
AKR1C2 P52895 1/20 0.40
AKR1C1 Q04828 1/20 0.40
DCLK1 O15075 1/20 0.40
PRKD3 O94806 1/20 0.40
MAP4K4 O95819 1/20 0.40
CHEK2 O96017 1/20 0.40
CSF1R P07333 1/20 0.40
FER P16591 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29635316 1.00 ALDH1A1 (0.58) ALDH1A1MAPK1PTPRCPTGDR2BACE1
SCHEMBL10479111 0.85 ALOX15 (0.44) ALDH1A1MAPK1PTPRCALOX15CYP2A6
SCHEMBL29789063 0.84 ALDH1A1 (0.44) ALDH1A1MAPK1ALOX15NPC1TP53
SCHEMBL364027 0.83 MAPK1 (0.52) ALDH1A1MAPK1PTPRCPTGDR2BACE1
Water SCHEMBL22361233 0.83 ALOX15 (0.42) ALDH1A1MAPK1PTPRCALOX15CYP2A6
SCHEMBL19190198 0.83 PTPRC (0.56) ALDH1A1MAPK1PTPRCPTGDR2BACE1
SCHEMBL30006434 0.83 MAPK1 (0.52) ALDH1A1MAPK1PTPRCPTGDR2BACE1
Water SCHEMBL28671726 0.82 ALDH1A1 (0.43) ALDH1A1MAPK1ALOX15NPC1TP53
SCHEMBL24542622 0.81 ALDH1A1 (0.58) ALDH1A1MAPK1BACE1ALOX5CRHBP
SCHEMBL2715170 0.81 ALDH1A1 (0.58) ALDH1A1MAPK1BACE1ALOX5CRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104130249-B Benzimidazole compound and preparation method and application thereof 陕西科技大学 2017-04-26 CN claimed
CN-118290211-A Preparation method of high-purity p-terphenyl 中国船舶集团有限公司第七一八研究所 2024-07-05 CN disclosed
US-11832513-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2023-11-28 US disclosed
US-11832513-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2023-11-28 US disclosed
EP-4242286-A2 MATERIALS FOR ELECTRONIC DEVICES Merck Patent GmbH (DE) 2023-09-13 EP disclosed
EP-3714022-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-06-07 EP disclosed
CN-110317140-B Compound with arylamine and bis-dimethyl fluorene as cores and application thereof 江苏三月科技股份有限公司 2022-05-13 CN disclosed
CN-106631983-B Dendritic compound based on stilbene unit and organic electroluminescent device 中国科学院长春应用化学研究所 2021-09-21 CN disclosed
CN-112538022-A Novel hole transport material and application thereof 北京大学深圳研究生院 2021-03-23 CN disclosed
US-20200303654-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-09-24 US disclosed
US-4897238-A TENSILE STRENGTH, HEAT RESISTANCE KUREHA KAGAKU KOGYO K.K. (JP) 1990-01-30 US disclosed
US-4895912-A HEAT RESISTANCE KUREHA KAGAKU KOGYO K.K. (JP) 1990-01-23 US disclosed
US-4895892-A HEAT RESISTANT MOLDING MATERIALS KUREHA KAGAKU KOGYO K.K. (JP) 1990-01-23 US disclosed
US-4873283-A HEAT RESISTANCE AND STRENGTH KUREHA KAGAKU KOGYO K.K. (JP) 1989-10-10 US disclosed
US-4853487-A HYDROLYSIS OF BROMOBIPHENYLS RHONE-POULENC CHIMIE (FR) 1989-08-01 US disclosed
EP-0323180-A2 Coated metal body KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-07-05 EP disclosed
EP-0293116-A2 Melt-stable poly(arylene thioether-ketone) compositions KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-11-30 EP disclosed
EP-0293113-A2 Stretched poly(arylene thioether-ketone) films and production process thereof KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-11-30 EP disclosed
EP-0293118-A2 Molded or formed poly(arylene thioether-ketone) articles KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-11-30 EP disclosed
US-4223172-A DEHYDROGENATION HALOGENATIVE WITH PALLADIUM-PHOSPHINE COMPLEX CATALYST GULF RESEARCH & DEVELOPMENT COMPANY (US) 1980-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11832513-B2 Materials for electronic devices PNMT, DDT, COMT ALDH1A1 321/4885MAPK1 2720/4885PTPRC 1623/4885
US-20200303654-A1 MATERIALS FOR ELECTRONIC DEVICES PNMT, DDT, COMT ALDH1A1 321/4885MAPK1 2720/4885PTPRC 1623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.