SCHEMBL29635532

SCHEMBL29635532

COC(=O)C(C)(C)ON(c1ccc(C(=O)c2ccccc2)cc1)C(C)(C)C(=O)OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.50
NPC1 O15118 1/20 0.46
HPGD P15428 1/20 0.46
RAB9A P51151 1/20 0.46
SRC P12931 1/20 0.41
PPARG P37231 3/20 0.38
PPARD Q03181 2/20 0.38
PPARA Q07869 2/20 0.38
ALDH1A1 P00352 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
SRD5A2 P31213 1/20 0.38
ABCC9 O60706 2/20 0.37
ABCC8 Q09428 2/20 0.37
KCNJ11 Q14654 2/20 0.37
PDK1 Q15118 2/20 0.37
PDK2 Q15119 2/20 0.37
PDK3 Q15120 2/20 0.37
KCNJ8 Q15842 2/20 0.37
PDK4 Q16654 2/20 0.37
ABCB11 O95342 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23355253 0.80 ELANE (0.55) ELANENPC1HPGDRAB9ASRC
SCHEMBL11441181 0.74 ELANE (0.66) ELANEHPGDSRCPPARGPPARA
SCHEMBL329718 0.68 HPGD (0.63) ELANENPC1HPGDRAB9AALDH1A1
SCHEMBL8982998 0.68 HPGD (0.63) ELANENPC1HPGDRAB9AALDH1A1
SCHEMBL10483697 0.67 ELANE (1.00) ELANENPC1PPARAL3MBTL1MEN1
Benzophenone SCHEMBL9304441 0.67 ALDH1A1 (0.64) ELANENPC1HPGDRAB9APPARA
SCHEMBL10944759 0.66 CES1 (0.53) ELANENPC1HPGDRAB9ASRC
Benzophenone SCHEMBL2955921 0.66 ALDH1A1 (0.78) ELANENPC1HPGDRAB9AALDH1A1
SCHEMBL4595696 0.66 RAB9A (0.60) ELANENPC1HPGDRAB9AALDH1A1
SCHEMBL43585 0.65 HPGD (1.00) NPC1HPGDRAB9AALDH1A1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4514595-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
EP-4240578-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2024-12-18 EP claimed
WO-2023209570-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO claimed
EP-4240578-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2023-09-13 EP claimed
WO-2022097048-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-05-12 WO claimed
EP-4514595-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP disclosed
WO-2023209570-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO disclosed
EP-4240578-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2023-09-13 EP disclosed
WO-2022097048-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-05-12 WO disclosed