SCHEMBL23355253

SCHEMBL23355253

COC(=O)C(C)(C)N(O)c1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.55
HPGD P15428 3/20 0.51
RAB9A P51151 2/20 0.51
NPC1 O15118 1/20 0.51
SRC P12931 1/20 0.45
ALDH1A1 P00352 4/20 0.42
SRD5A2 P31213 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
KCNN4 O15554 1/20 0.41
MAPK13 O15264 1/20 0.41
MAPK12 P53778 1/20 0.41
MAPK11 Q15759 1/20 0.41
MAPK14 Q16539 1/20 0.41
TSHR P16473 1/20 0.41
MAPT P10636 1/20 0.41
ABCC9 O60706 2/20 0.40
ABCC8 Q09428 2/20 0.40
KCNJ11 Q14654 2/20 0.40
PDK1 Q15118 2/20 0.40
PDK2 Q15119 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29635532 0.80 ELANE (0.50) ELANEHPGDRAB9ANPC1SRC
SCHEMBL10062370 0.73 HPGD (0.56) ELANEHPGDRAB9ANPC1ALDH1A1
SCHEMBL11441181 0.72 ELANE (0.66) ELANEHPGDSRCTSHRMAPT
SCHEMBL329718 0.72 HPGD (0.63) ELANEHPGDRAB9ANPC1ALDH1A1
SCHEMBL8982998 0.72 HPGD (0.63) ELANEHPGDRAB9ANPC1ALDH1A1
SCHEMBL10483697 0.71 ELANE (1.00) ELANENPC1L3MBTL1MAPT
Benzophenone SCHEMBL9304441 0.70 ALDH1A1 (0.64) ELANEHPGDRAB9ANPC1ALDH1A1
Benzophenone SCHEMBL2955921 0.70 ALDH1A1 (0.78) ELANEHPGDRAB9ANPC1ALDH1A1
Michler'S Ketone SCHEMBL3324670 0.69 HPGD (1.00) HPGDRAB9ANPC1ALDH1A1SRD5A2
SCHEMBL43585 0.69 HPGD (1.00) HPGDRAB9ANPC1ALDH1A1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814336-B2 Oligomeric alkoxy amines ARKEMA FRANCE (FR) 2023-11-14 US disclosed
US-20210139415-A1 OLIGOMERIC ALKOXYAMINES ARKEMA FRANCE (FR) 2021-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210139415-A1 OLIGOMERIC ALKOXYAMINES ALKBH3, ALK, ALKBH2 ELANE 2465/4885HPGD 4033/4885RAB9A 4331/4885
US-11814336-B2 Oligomeric alkoxy amines ALKBH3, ALK, PNMT ELANE 2790/4885HPGD 4064/4885RAB9A 4096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.