SCHEMBL29635879

SCHEMBL29635879

O=C(Nc1ccc(C(F)(F)F)cn1)N1CCN(c2ncccc2C(F)(F)F)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 10/20 1.00
GAA P10253 1/20 0.64
NPSR1 Q6W5P4 1/20 0.61
HSD17B10 Q99714 1/20 0.61
CA12 O43570 1/20 0.60
CA1 P00915 1/20 0.60
CA2 P00918 1/20 0.60
CA9 Q16790 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29389124 1.00 TRPV1 (1.00) TRPV1GAANPSR1HSD17B10CA12
SCHEMBL138342 1.00 TRPV1 (1.00) TRPV1GAANPSR1HSD17B10CA12
SCHEMBL4262912 0.88 TRPV1 (0.79) TRPV1
SCHEMBL4265025 0.81 TRPV1 (0.78) TRPV1GAANPSR1HSD17B10CA12
SCHEMBL14422335 0.79 TRPV1 (0.65) TRPV1
SCHEMBL4262793 0.78 TRPV1 (0.82) TRPV1GAANPSR1HSD17B10CA12
SCHEMBL3712104 0.77 TRPV1 (0.80) TRPV1GAANPSR1HSD17B10CA12
SCHEMBL4269392 0.77 TRPV1 (0.73) TRPV1GAANPSR1HSD17B10CA12
SCHEMBL16690819 0.77 TRPV1 (0.66) TRPV1GAANPSR1HSD17B10CA12
SCHEMBL3095680 0.76 HSD11B1 (0.76) TRPV1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250017954-A1 Formulations and Methods for Treating Symptoms of Menopause Kindra Corporation (US) 2025-01-16 US claimed
US-20240408041-A1 COMPOSITIONS AND METHODS FOR TREATING CANNABINOID HYPEREMESIS SYNDROME HABBOUSHE JOSEPH (US) 2024-12-12 US claimed
EP-4433045-A2 FORMULATIONS AND METHODS FOR TREATING SYMPTOMS OF MENOPAUSE KINDRA CORPORATION (US) 2024-09-25 EP claimed
CN-118510501-A Formulations and methods for treating climacteric symptoms 金卓拉公司 2024-08-16 CN claimed
WO-2023091628-A2 FORMULATIONS AND METHODS FOR TREATING SYMPTOMS OF MENOPAUSE PG13 LAUNCHPAD ALPHA, INC. DBA KINDRA (US) 2023-05-25 WO claimed
US-20260048008-A1 ORGANOGELS FOR SUSTAINED DRUG DELIVERY, METHODS OF PREPARATION AND USE THEREOF OCULAR THERAPEUTIX INC (US) 2026-02-19 US disclosed
EP-4695324-A1 BIO-ORTHOGONAL HYDROGELS FOR SUSTAINED RELEASE DRUG DELIVERY Ocular Therapeutix, Inc. (US) 2026-02-18 EP disclosed
EP-4683964-A2 POLY(ETHYLENE GLYCOL) BASED DENDRIMER-LIKE HYPERBRANCHED MACROMOLECULES, METHODS OF PREPARATION AND USE THEREOF Ocular Therapeutix, Inc. (US) 2026-01-28 EP disclosed
EP-4568658-A1 ORGANOGELS FOR SUSTAINED DRUG DELIVERY, METHODS OF PREPARATION AND USE THEREOF Ocular Therapeutix, Inc. (US) 2025-06-18 EP disclosed
CN-119947711-A Organogels for sustained drug delivery, methods of preparation and uses thereof 视尔普斯眼科公司 2025-05-06 CN disclosed
US-20250140406-A1 CLASSIFYING TUMORS AND PREDICTING RESPONSIVENESS INSIGHT MOLECULAR DIAGNOSTICS INC. 2025-05-01 US disclosed
US-20250017954-A1 Formulations and Methods for Treating Symptoms of Menopause Kindra Corporation (US) 2025-01-16 US disclosed
CN-118510501-A Formulations and methods for treating climacteric symptoms 金卓拉公司 2024-08-16 CN disclosed
WO-2024035690-A1 ORGANOGELS FOR SUSTAINED DRUG DELIVERY, METHODS OF PREPARATION AND USE THEREOF OCULAR THERAPEUTIX, INC. (US) 2024-02-15 WO disclosed
WO-2023148231-A1 MULTIDOSE OPHTHALMIC COMPOSITIONS Oculis SA (CH) 2023-08-10 WO disclosed
WO-2023091628-A2 FORMULATIONS AND METHODS FOR TREATING SYMPTOMS OF MENOPAUSE PG13 LAUNCHPAD ALPHA, INC. DBA KINDRA (US) 2023-05-25 WO disclosed
CN-114533816-B Medicament for treating chronic cough and pharmaceutical composition, preparation method and application thereof 广州医科大学附属第一医院(广州呼吸中心) 2022-11-22 CN disclosed
US-20220244263-A1 METHODS FOR TREATING SMALL CELL NEUROENDOCRINE AND RELATED CANCERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-08-04 US disclosed
CN-114533816-A Medicament for treating chronic cough and pharmaceutical composition, preparation method and application thereof 广州医科大学附属第一医院(广州呼吸中心) 2022-05-27 CN disclosed
US-11339122-B2 hTRPV1 chemical agents University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2022-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048008-A1 ORGANOGELS FOR SUSTAINED DRUG DELIVERY, METHODS OF PREPARATION AND USE THEREOF KIT, IL33, LY96 TRPV1 2697/4885GAA 1036/4885NPSR1 3537/4885
US-11339122-B2 hTRPV1 chemical agents TRPV1, TRPA1, TRPV4 TRPV1 1/4885GAA 4709/4885NPSR1 322/4885
US-20240408041-A1 COMPOSITIONS AND METHODS FOR TREATING CANNABINOID HYPEREMESIS SYNDROME CNR2, TRPV1, CNR1 TRPV1 2/4885GAA 2771/4885NPSR1 67/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.