Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KLK7 | P49862 | 1/20 | 0.53 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | PI4KA | P42356 | 1/20 | 0.48 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.48 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11387427 | 0.80 | CYP1A2 (0.53) | ALDH1A1KMT2AKLK7KLK14KLK5 | |
| SCHEMBL11382140 | 0.79 | CYP1A2 (0.52) | ALDH1A1KMT2AKLK7KLK14KLK5 | |
| SCHEMBL21597614 | 0.76 | NPC1 (0.41) | ALDH1A1KMT2AGAAMAPTHTT | |
| SCHEMBL544340 | 0.75 | MAPK1 (0.41) | KMT2ASMN1; SMN2MAPTPI4KAPI4K2B | |
| Hydrochloric Acid SCHEMBL11377545 | 0.75 | SMN1; SMN2 (0.59) | ALDH1A1KMT2ACYP1A2CYP2C9SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11391773 | 0.75 | CYP1A2 (0.51) | ALDH1A1CYP1A2CYP2C9SMN1; SMN2GAA | |
| SCHEMBL11375905 | 0.73 | ALDH1A1 (0.48) | ALDH1A1KMT2ACYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL10868824 | 0.73 | CYP1A2 (0.46) | ALDH1A1KMT2AKLK7KLK14KLK5 | |
| Hydrochloric Acid SCHEMBL11378680 | 0.72 | ALDH1A1 (0.47) | ALDH1A1KMT2ACYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL17844189 | 0.71 | MAPT (0.50) | ALDH1A1KMT2ACYP1A2CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11351164-B2 | Inhibitors of indoleamine 2,3-dioxygenase and methods of their use | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11351164-B2 | Inhibitors of indoleamine 2,3-dioxygenase and methods of their use | IDO1, IDO2, INMT | ALDH1A1 868/4885KMT2A 469/4885KLK7 3611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.