Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576586 | 0.80 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBHTT | |
| SCHEMBL21597614 | 0.79 | NPC1 (0.41) | MAPK1MAPTHTTKMT2ANOTUM | |
| SCHEMBL8845189 | 0.76 | TDP1 (0.45) | EGFRMAPTNOTUM | |
| SCHEMBL29636320 | 0.75 | ALDH1A1 (0.53) | MAPK1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL28864107 | 0.74 | MAPK1 (0.41) | MAPK1TSHRHTTOPRD1SMN1; SMN2 | |
| SCHEMBL22827475 | 0.74 | HTT (0.44) | MAPK1HTTOPRD1SMN1; SMN2OPRM1 | |
| SCHEMBL1151405 | 0.74 | MAPK1 (0.41) | MAPK1MAPTFGFR1HTTOPRD1 | |
| SCHEMBL10166461 | 0.74 | OPRD1 (0.42) | MAPK1MAPTFGFR1HTTOPRD1 | |
| SCHEMBL8957749 | 0.74 | MAPK1 (0.41) | MAPK1FGFR1HTTOPRD1SMN1; SMN2 | |
| SCHEMBL28235351 | 0.74 | MAPK1 (0.49) | MAPK1FGFR1HTTOPRD1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12121026-B1 | N-[(1-phenyl-4H-1,2,4-triazol-3-yl) carbamothioyl]benzamide as an eco-friendly insecticidal agent against spodoptera littoralis | King Faisal University (SA) | 2024-10-22 | — | — | US | claimed |
| US-12121026-B1 | N-[(1-phenyl-4H-1,2,4-triazol-3-yl) carbamothioyl]benzamide as an eco-friendly insecticidal agent against spodoptera littoralis | King Faisal University (SA) | 2024-10-22 | — | — | US | disclosed |
| US-11998012-B1 | N-[(1-phenyl-4H-1,2,4-triazol-3-yl)carbamothioyl]benzamide as an eco-friendly insecticidal agent against Spodoptera littoralis | King Faisal University (SA) | 2024-06-04 | — | — | US | disclosed |
| EP-2991128-A1 | ORGANIC LIGHT-EMITTING DEVICE | Samsung Electronics Co., Ltd. (KR) | 2016-03-02 | — | — | EP | disclosed |
| WO-2015105315-A1 | FUSED-RING COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | 삼성에스디아이 주식회사 | 2015-07-16 | — | — | WO | disclosed |
| US-8980837-B2 | Inhibitors of IAP | GENENTECH, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-8980837-B2 | Inhibitors of IAP | GENENTECH, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-8980837-B2 | Inhibitors of IAP | GENENTECH, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-8907092-B2 | Inhibitors of IAP | GENENTECH, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-8907092-B2 | Inhibitors of IAP | GENENTECH, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-20070299052-A1 | Inhibitors of IAP | GENENTECH, INC. (US) | 2007-12-27 | — | — | US | disclosed |
| US-20070299052-A1 | Inhibitors of IAP | GENENTECH, INC. (US) | 2007-12-27 | — | — | US | disclosed |
| US-7244851-B2 | 1-[2-Cyclohexyl-2-(2-methylamino-propionylamino)-acetyl]-pyrrolidine-2-carboxylic acid (2-phenyl-2H-pyrazol-3-yl)-amide; inhibitors of IAP, for treating malignancies | GENENTECH, INC. (US) | 2007-07-17 | — | — | US | disclosed |
| US-7244851-B2 | 1-[2-Cyclohexyl-2-(2-methylamino-propionylamino)-acetyl]-pyrrolidine-2-carboxylic acid (2-phenyl-2H-pyrazol-3-yl)-amide; inhibitors of IAP, for treating malignancies | GENENTECH, INC. (US) | 2007-07-17 | — | — | US | disclosed |
| US-7244851-B2 | 1-[2-Cyclohexyl-2-(2-methylamino-propionylamino)-acetyl]-pyrrolidine-2-carboxylic acid (2-phenyl-2H-pyrazol-3-yl)-amide; inhibitors of IAP, for treating malignancies | GENENTECH, INC. (US) | 2007-07-17 | — | — | US | disclosed |
| EP-1778718-A1 | INHIBITORS OF IAP | Genentech, Inc. (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006014361-A1 | INHIBITORS OF IAP | GENENTECH, INC. (US) | 2006-02-09 | — | — | WO | disclosed |
| US-20060014700-A1 | 1-[2-Cyclohexyl-2-(2-methylamino-propionylamino)-acetyl]-pyrrolidine-2-carboxylic acid (2-phenyl-2H-pyrazol-3-yl)-amide; inhibitors of IAP, for treating malignancies | GENENTECH, INC. (US) | 2006-01-19 | — | — | US | disclosed |
| US-4659727-A | ANTIARTHRITIC AGENTS | MAY & BAKER LIMITED (GB) | 1987-04-21 | — | — | US | disclosed |
| EP-0174832-A2 | Ethene derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299052-A1 | Inhibitors of IAP | XIAP, BIRC5, BIRC3 | MAPK1 3051/4885EGFR 2722/4885PI4KA 2277/4885 |
| US-11998012-B1 | N-[(1-phenyl-4H-1,2,4-triazol-3-yl)carbamothioyl]benzamide as an eco-friendly insecticidal agent against Spodoptera littoralis | NIT2, AADAC, SPOUT1 | MAPK1 3668/4885EGFR 4819/4885PI4KA 1425/4885 |
| US-20060014700-A1 | 1-[2-Cyclohexyl-2-(2-methylamino-propionylamino)-acetyl]-pyrrolidine-2-carboxylic acid (2-phenyl-2H-pyrazol-3-yl)-amide; inhibitors of IAP, for treating malignancies | BIRC5, BIRC2, XIAP | MAPK1 2642/4885EGFR 2482/4885PI4KA 1469/4885 |
| US-12121026-B1 | N-[(1-phenyl-4H-1,2,4-triazol-3-yl) carbamothioyl]benzamide as an eco-friendly insecticidal agent against spodoptera littoralis | NIT2, AADAC, SPOUT1 | MAPK1 3668/4885EGFR 4819/4885PI4KA 1425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.