Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638107 | 0.82 | EGFR (0.35) | EGFR | |
| SCHEMBL29638104 | 0.70 | MAPKAPK2 (0.45) | EGFR | |
| SCHEMBL29638115 | 0.67 | ALDH1A1 (0.35) | EGFR | |
| SCHEMBL29638105 | 0.66 | ALDH1A1 (0.34) | EGFR | |
| SCHEMBL29638106 | 0.65 | EGFR (0.48) | EGFR | |
| SCHEMBL21557748 | 0.60 | TGM2 (0.41) | EGFR | |
| SCHEMBL27004222 | 0.59 | EGFR (0.60) | EGFR | |
| SCHEMBL23480108 | 0.58 | EGFR (0.80) | EGFR | |
| SCHEMBL14150146 | 0.58 | EGFR (0.65) | EGFR | |
| SCHEMBL19958218 | 0.57 | TGM2 (0.58) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110950871-B | 2-substituted-4-arylamino pyrazolotriazine derivative and application thereof in preparing antitumor drugs | 陕西师范大学 | 2022-05-17 | — | — | CN | claimed |
| CN-110950871-B | 2-substituted-4-arylamino pyrazolotriazine derivative and application thereof in preparing antitumor drugs | 陕西师范大学 | 2022-05-17 | — | — | CN | disclosed |