Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.45 |
| ▸ | KDM1A | O60341 | 5/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6217782 | 0.81 | CA12 (0.57) | KDM4ESMN1; SMN2HIF1ACASP6CA12 | |
| SCHEMBL3918261 | 0.78 | KDM4E (0.58) | HDAC1HDAC6HDAC2HDAC8KDM4E | |
| SCHEMBL679952 | 0.69 | CYP19A1 (0.55) | KDM1AKDM4ESMN1; SMN2HIF1ACASP6 | |
| SCHEMBL31551042 | 0.69 | CYP19A1 (0.55) | KDM1AKDM4ESMN1; SMN2HIF1ACASP6 | |
| SCHEMBL619724 | 0.69 | CES2 (0.50) | HDAC1HDAC6KDM4EMPOGAA | |
| SCHEMBL28348282 | 0.69 | MAOA (0.45) | KDM1AHDAC8MAOAMAOBKDM4E | |
| Hydrochloric Acid SCHEMBL15621988 | 0.68 | CYP19A1 (0.53) | KDM1AKDM4ESMN1; SMN2HIF1ACASP6 | |
| SCHEMBL27654823 | 0.68 | CYP19A1 (0.53) | KDM1AKDM4ESMN1; SMN2HIF1ACASP6 | |
| SCHEMBL23263176 | 0.67 | CASP6 (0.46) | MAOAMAOBGAASMN1; SMN2CASP6 | |
| Hydrochloric Acid SCHEMBL28385733 | 0.67 | MAOA (0.43) | KDM1AHDAC8MAOAMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110317177-B | Preparation method of pyrimidine salicylic acid oxime ester compound and application of pyrimidine salicylic acid oxime ester compound as herbicide | 常州大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-110317177-B | Preparation method of pyrimidine salicylic acid oxime ester compound and application of pyrimidine salicylic acid oxime ester compound as herbicide | 常州大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-110317177-B | Preparation method of pyrimidine salicylic acid oxime ester compound and application of pyrimidine salicylic acid oxime ester compound as herbicide | 常州大学 | 2022-05-17 | — | — | CN | disclosed |