SCHEMBL29638155

SCHEMBL29638155

Fc1cc(Cl)c(Cl)cc1F

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AHR P35869 4/20 0.41
MAPK1 P28482 1/20 0.41
FLT1 P17948 1/20 0.39
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
KDM1A O60341 2/20 0.37
KDM1B Q8NB78 1/20 0.37
HPGD P15428 3/20 0.37
TSHR P16473 3/20 0.37
HSD17B10 Q99714 2/20 0.37
TP53 P04637 1/20 0.37
ALDH1A1 P00352 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
MAPT P10636 1/20 0.35
CYP3A4 P08684 2/20 0.35
GAA P10253 1/20 0.33
SLC2A1 P11166 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9182733 1.00 AHR (0.41) AHRMAPK1FLT1POLBAPEX1
SCHEMBL7940907 0.85 AHR (0.44) AHRMAPK1FLT1KDM1AKDM1B
SCHEMBL811929 0.85 KDM1A (0.44) POLBAPEX1KDM1AKDM1BHPGD
SCHEMBL29362089 0.85 KDM1A (0.44) POLBAPEX1KDM1AKDM1BHPGD
SCHEMBL23351729 0.83 KDM1A (0.48) AHRMAPK1POLBAPEX1KDM1A
SCHEMBL18893969 0.77 HSD17B10 (0.55) POLBAPEX1HPGDTSHRHSD17B10
SCHEMBL7062222 0.77 CD44 (0.48) POLBAPEX1ALDH1A1CYP3A4GAA
SCHEMBL1759465 0.77 AHR (0.46) AHRPOLBAPEX1KDM1AKDM1B
SCHEMBL13664729 0.77 ALDH1A1 (0.34) AHRMAPK1FLT1KDM1AKDM1B
SCHEMBL18129365 0.77 POLB (0.32) POLBAPEX1KDM1AKDM1BHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112707807-B Preparation method of 4, 5-difluorophthalic acid 苏州当量生物医药有限公司 2022-06-07 CN claimed
CN-109836419-B9 Novel heterocyclic compound and organic light-emitting element using same 株式会社LG化学 2022-08-05 CN disclosed
CN-110740998-B Compound and organic light emitting device including the same 株式会社LG化学 2022-07-22 CN disclosed
CN-109836419-B Novel heterocyclic compound and organic light-emitting element using same 株式会社LG化学 2022-07-01 CN disclosed
CN-112707807-B Preparation method of 4, 5-difluorophthalic acid 苏州当量生物医药有限公司 2022-06-07 CN disclosed
CN-110494430-B Novel compound and organic light-emitting element using same 株式会社LG化学 2022-05-27 CN disclosed
CN-110291077-B Novel heterocyclic compound and organic light emitting device comprising the same 株式会社LG化学 2022-05-17 CN disclosed