Sugi Predict

Sugi Predict / Compounds / SCHEMBL1759465

SCHEMBL1759465

SCHEMBL1759465

Fc1cc(Cl)c(Br)cc1F

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ AHR P35869 3/20 0.46
▸ CSNK2A1 P68400 1/20 0.37
▸ KDM1A O60341 6/20 0.36
▸ KDM1B Q8NB78 4/20 0.36
▸ PLAU P00749 1/20 0.34
▸ ELANE P08246 1/20 0.34
▸ POLB P06746 1/20 0.32
▸ APEX1 P27695 1/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ HPGD P15428 2/20 0.31
▸ KCNH2 Q12809 2/20 0.31
▸ CA1 P00915 1/20 0.31
▸ CA2 P00918 1/20 0.31
▸ CA9 Q16790 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.30
▸ TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17543931 0.86 AHR (0.44) AHRCSNK2A1KDM1AKDM1BPLAU
SCHEMBL21218760 0.86 AHR (0.44) AHRCSNK2A1KDM1AKDM1BPLAU
SCHEMBL30214380 0.86 AHR (0.44) AHRCSNK2A1KDM1AKDM1BNPC1
SCHEMBL8458346 0.86 AHR (0.44) AHRCSNK2A1KDM1AKDM1BNPC1
SCHEMBL31070107 0.80 KDM1A (0.44) AHRKDM1AKDM1BPLAUELANE
SCHEMBL1397113 0.80 KDM1A (0.44) AHRKDM1AKDM1BPLAUELANE
SCHEMBL23706575 0.79 AHR (0.39) AHRCSNK2A1KDM1AKDM1BPOLB
SCHEMBL22289792 0.79 AHR (0.39) AHRCSNK2A1KDM1AKDM1BNPC1
SCHEMBL22123164 0.79 TSHR (0.40) AHRCSNK2A1KDM1AKDM1BNPC1
SCHEMBL22289313 0.79 AHR (0.39) AHRCSNK2A1KDM1AKDM1BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6100492-A — — None — — JP disclosed
US-12268687-B2 Compounds and uses thereof JANSSEN PHARMACEUTICA NV (BE) 2025-04-08 — — US disclosed
US-20250034125-A1 COMPOUNDS AND USES THEREOF JANSSEN PHARMACEUTICA NV (BE) 2025-01-30 — — US disclosed
US-20250034124-A1 COMPOUNDS AND USES THEREOF JANSSEN PHARMACEUTICA NV (BE) 2025-01-30 — — US disclosed
US-12098146-B2 Compounds and uses thereof JANSSEN PHARMACEUTICA NV (BE) 2024-09-24 — — US disclosed
US-20230116101-A1 COMPOUNDS AND USES THEREOF YUMANITY THERAPEUTICS, INC. 2023-04-13 — — US disclosed
CN-113906019-A Compound and use thereof 优曼尼蒂治疗公司 2022-01-07 — — CN disclosed
EP-3914593-A1 COMPOUNDS AND USES THEREOF Yumanity Therapeutics, Inc. (US) 2021-12-01 — — EP disclosed
WO-2021097240-A1 COMPOUNDS AND USES THEREOF YUMANITY THERAPEUTICS, INC. (US) 2021-05-20 — — WO disclosed
WO-2021097240-A1 COMPOUNDS AND USES THEREOF YUMANITY THERAPEUTICS, INC. (US) 2021-05-20 — — WO disclosed
US-9573881-B2 Halogenated aniline and method for producing same NIPPON SODA CO., LTD. (JP) 2017-02-21 — — US disclosed
US-20170029361-A1 HALOGENATED ANILINE AND METHOD FOR PRODUCING SAME NIPPON SODA CO., LTD. (JP) 2017-02-02 — — US disclosed
EP-2940002-B1 HALOGENATED ANILINE AND METHOD FOR PRODUCING SAME NIPPON SODA CO (JP) 2016-12-14 — — EP disclosed
US-20150329472-A1 HALOGENATED ANILINE AND METHOD FOR PRODUCING SAME NIPPON SODA CO., LTD. (JP) 2015-11-19 — — US disclosed
EP-2940002-A1 HALOGENATED ANILINE AND METHOD FOR PRODUCING SAME Nippon Soda Co., Ltd. (JP) 2015-11-04 — — EP disclosed
WO-2011057956-A1 BENZISOXAZOLE ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS F. HOFFMANN-LA ROCHE AG (CH) 2011-05-19 — — WO disclosed
US-20110112158-A1 BENZISOXAZOLE ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS BOLIN DAVID ROBERT 2011-05-12 — — US disclosed
JP-H06100492-A PRODUCTION OF 2-CHLORO-4,5-DIFLUOROBENZOIC ACID TOHKEM PROD:KK 1994-04-12 — — JP disclosed
EP-0063066-B1 PROCESS FOR THE ISOMERIZATION OF BROMOHALOGEN BENZENES RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-06-20 — — EP disclosed
EP-0063066-A1 Process for the isomerization of bromohalogen benzenes RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1982-10-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250034124-A1 COMPOUNDS AND USES THEREOF NLN, BDNF, NQO1 AHR 2705/4885CSNK2A1 2968/4885KDM1A 1876/4885
US-12268687-B2 Compounds and uses thereof NLN, BDNF, NQO1 AHR 2705/4885CSNK2A1 2968/4885KDM1A 1876/4885
US-20170029361-A1 HALOGENATED ANILINE AND METHOD FOR PRODUCING SAME TPO, CYP1A2, XDH AHR 172/4885CSNK2A1 229/4885KDM1A 1967/4885
US-20110112158-A1 BENZISOXAZOLE ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS GYS2, GYS1, PYGL AHR 4138/4885CSNK2A1 315/4885KDM1A 2798/4885
US-20150329472-A1 HALOGENATED ANILINE AND METHOD FOR PRODUCING SAME TPO, CYP1A2, XDH AHR 172/4885CSNK2A1 229/4885KDM1A 1967/4885
US-20230116101-A1 COMPOUNDS AND USES THEREOF NLN, BDNF, NQO1 AHR 2705/4885CSNK2A1 2968/4885KDM1A 1876/4885
US-20250034125-A1 COMPOUNDS AND USES THEREOF NLN, BDNF, NQO1 AHR 2705/4885CSNK2A1 2968/4885KDM1A 1876/4885
US-12098146-B2 Compounds and uses thereof NLN, BDNF, NQO1 AHR 2705/4885CSNK2A1 2968/4885KDM1A 1876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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