Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | PDXK | O00764 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038760 | 1.00 | KDM4E (0.41) | KDM4EPDXKALDH1A1HPGDHSD17B10 | |
| SCHEMBL16796089 | 0.79 | PDXK (0.31) | PDXK | |
| SCHEMBL14048734 | 0.79 | DHFR (0.38) | KDM4EPDXKALDH1A1HPGDHSD17B10 | |
| SCHEMBL2493947 | 0.77 | LMNA (0.39) | KDM4EPDXKALDH1A1HPGDHSD17B10 | |
| SCHEMBL23059363 | 0.77 | LMNA (0.43) | KDM4EPDXKALDH1A1HPGDHSD17B10 | |
| SCHEMBL6218700 | 0.76 | AURKA (0.41) | PDXK | |
| SCHEMBL16796162 | 0.74 | LMNA (0.46) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL19685264 | 0.71 | LMNA (0.35) | KDM4EPDXKALDH1A1HPGDHSD17B10 | |
| SCHEMBL6673043 | 0.69 | — | — | |
| SCHEMBL9844344 | 0.69 | AGTR1 (0.40) | KDM4EPDXKALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4722212-A1 | NOVEL COMPOUND FOR INHIBITING PROTEIN KINASES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Magicbullettherapeutics Co., Ltd. (KR) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024242495-A1 | NOVEL COMPOUND FOR INHIBITING PROTEIN KINASES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 매직불릿테라퓨틱스 | 2024-11-28 | — | — | WO | disclosed |
| WO-2024044731-A1 | DIAZEPINO-THIENO-QUINOXALINE COMPOUNDS AND THEIR USE IN THERAPY | MATCHPOINT THERAPEUTICS INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| CN-113527311-B | FGFR4 inhibitor, composition and application thereof in preparation of medicines | 中南大学湘雅医院 | 2022-05-06 | — | — | CN | disclosed |