Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 12/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 3/20 | 0.43 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24557316 | 1.00 | ABL1 (0.47) | ABL1NPC1RAB9ASMN1; SMN2TYK2 | |
| SCHEMBL29638315 | 0.88 | ABL1 (0.46) | ABL1NPC1RAB9ASMN1; SMN2TYK2 | |
| SCHEMBL24557318 | 0.88 | ABL1 (0.46) | ABL1NPC1RAB9ASMN1; SMN2TYK2 | |
| SCHEMBL29638378 | 0.87 | TYK2 (0.46) | ABL1SMN1; SMN2TYK2 | |
| SCHEMBL29638360 | 0.86 | TYK2 (0.50) | ABL1NPC1RAB9ASMN1; SMN2TYK2 | |
| SCHEMBL29638385 | 0.84 | ABL1 (0.47) | ABL1NPC1RAB9AMAP4K1 | |
| SCHEMBL24557310 | 0.79 | PIK3CD (0.46) | ABL1MAP4K1 | |
| SCHEMBL29638382 | 0.78 | ABL1 (0.53) | ABL1NPC1RAB9ATYK2PKM | |
| SCHEMBL24557247 | 0.78 | ABL1 (0.48) | ABL1NPC1RAB9AMAP4K1LMNA | |
| SCHEMBL29638459 | 0.78 | ABL1 (0.55) | ABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |