Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 8/20 | 0.34 |
| ▸ | LYN | P07948 | 3/20 | 0.34 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | YES1 | P07947 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 1/20 | 0.32 |
| ▸ | FGR | P09769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638528 | 0.89 | TYK2 (0.33) | TP53TYK2LYNBTKSRC | |
| SCHEMBL29638438 | 0.89 | TYK2 (0.36) | TP53TYK2JAK1 | |
| SCHEMBL24557361 | 0.86 | MAPT (0.45) | ABCG2TYK2LYNSRCPOLB | |
| SCHEMBL29638464 | 0.86 | NPC1 (0.41) | TP53TYK2LYNBTKSRC | |
| SCHEMBL24557258 | 0.86 | NPC1 (0.41) | TP53TYK2LYNBTKSRC | |
| SCHEMBL24557263 | 0.85 | TYK2 (0.39) | ABCG2TYK2BTKSRCPOLB | |
| SCHEMBL29638451 | 0.85 | TYK2 (0.39) | ABCG2TYK2BTKSRCPOLB | |
| SCHEMBL29638412 | 0.85 | AKR1C3 (0.44) | TP53TYK2LYNSRCPOLB | |
| SCHEMBL29638325 | 0.85 | TP53 (0.39) | TP53TYK2LYNSRCPOLB | |
| SCHEMBL24557308 | 0.85 | TYK2 (0.40) | ABCG2TP53TYK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |