Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PLK1 | P53350 | 3/20 | 0.34 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638370 | 0.91 | PLK1 (0.44) | MAPTPLK1TYK2JAK1ABCG2 | |
| SCHEMBL29638374 | 0.87 | PLK1 (0.34) | MAPTPLK1TYK2JAK1 | |
| SCHEMBL29638354 | 0.86 | NPC1 (0.35) | MAPTTYK2JAK1 | |
| SCHEMBL29638362 | 0.86 | NPC1 (0.35) | MAPTTYK2JAK1 | |
| SCHEMBL29638381 | 0.84 | MAPK1 (0.33) | MAPTTYK2JAK1 | |
| SCHEMBL29638348 | 0.80 | PLK1 (0.34) | MAPTPLK1TYK2JAK1 | |
| SCHEMBL29638383 | 0.79 | RARG (0.36) | SLC34A1EIF2AK4AXLTYRO3MERTK | |
| SCHEMBL24557251 | 0.71 | JAK2 (0.37) | SLC34A1MAPTTYK2JAK2JAK1 | |
| SCHEMBL29638415 | 0.71 | JAK2 (0.37) | SLC34A1MAPTTYK2JAK2JAK1 | |
| SCHEMBL29638408 | 0.71 | PLK1 (0.36) | MAPTPLK1TYK2TSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |