Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.34 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638370 | 0.85 | PLK1 (0.44) | PLK1TYK2JAK1MAPT | |
| SCHEMBL29638457 | 0.80 | SLC34A1 (0.34) | PLK1TYK2JAK1MAPT | |
| SCHEMBL29638354 | 0.80 | NPC1 (0.35) | TYK2JAK1MAPT | |
| SCHEMBL29638362 | 0.80 | NPC1 (0.35) | TYK2JAK1MAPT | |
| SCHEMBL29638381 | 0.79 | MAPK1 (0.33) | TYK2JAK1MAPT | |
| SCHEMBL29638374 | 0.79 | PLK1 (0.34) | PLK1TYK2JAK1MAPT | |
| SCHEMBL29638408 | 0.73 | PLK1 (0.36) | PLK1TYK2MAPT | |
| SCHEMBL29638328 | 0.73 | TYK2 (0.36) | TYK2JAK1 | |
| SCHEMBL29638526 | 0.66 | PLK1 (0.40) | PLK1MAPT | |
| SCHEMBL29638441 | 0.66 | MAP3K14 (0.35) | PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |