Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | TYK2 | P29597 | 2/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638457 | 0.87 | SLC34A1 (0.34) | PLK1MAPTTYK2JAK1 | |
| SCHEMBL29638354 | 0.86 | NPC1 (0.35) | MAPTALDH1A1LMNATYK2JAK1 | |
| SCHEMBL29638362 | 0.86 | NPC1 (0.35) | MAPTALDH1A1LMNATYK2JAK1 | |
| SCHEMBL29638381 | 0.83 | MAPK1 (0.33) | MAPTTYK2JAK1MAPK1 | |
| SCHEMBL29638370 | 0.82 | PLK1 (0.44) | PLK1MAPTTYK2JAK1 | |
| SCHEMBL29638349 | 0.80 | PTGS2 (0.38) | ALOX5PIK3CA | |
| SCHEMBL29638348 | 0.79 | PLK1 (0.34) | PLK1MAPTTYK2JAK1 | |
| SCHEMBL29638469 | 0.72 | TYK2 (0.40) | ALDH1A1LMNAPOLBTYK2PIK3CA | |
| SCHEMBL29638473 | 0.72 | TYK2 (0.40) | ALDH1A1LMNAPOLBTYK2PIK3CA | |
| SCHEMBL29638408 | 0.70 | PLK1 (0.36) | PLK1MAPTALDH1A1TYK2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |