Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 3/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | CLK3 | P49761 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638579 | 0.90 | TRPA1 (0.44) | DYRK1AHDAC3HDAC1HDAC6TRPA1 | |
| SCHEMBL29638531 | 0.88 | HDAC3 (0.53) | HDAC3HDAC1HDAC6RAF1BRAF | |
| SCHEMBL29638608 | 0.88 | HDAC3 (0.46) | DYRK1AHDAC3HDAC1HDAC6RAF1 | |
| SCHEMBL29638530 | 0.82 | HDAC3 (0.44) | HDAC3HDAC1HDAC6RAF1BRAF | |
| SCHEMBL29638533 | 0.81 | NCOA1 (0.60) | KDRNCOA1NCOA3MAPTEGFR | |
| SCHEMBL26208965 | 0.79 | DYRK1A (0.43) | DYRK1ACLK1GSK3BCCNT1CDK9 | |
| Hydrochloric Acid SCHEMBL9378828 | 0.75 | ALDH1A1 (0.44) | CDK9EGFR | |
| SCHEMBL23624380 | 0.74 | TNF (0.50) | TRPA1KDRFLT1FGFR1EGFR | |
| SCHEMBL25375020 | 0.74 | MAPT (0.42) | DYRK1ACLK1GSK3BCCNT1CDK9 | |
| SCHEMBL29638713 | 0.74 | RAPGEF4 (0.41) | HDAC3HDAC1HDAC6TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089219-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |