SCHEMBL29639005

SCHEMBL29639005

COc1ccc(S(=O)(=O)Nc2nc(-c3cccc([N+](=O)[O-])c3)c(CN3CCCCC3)s2)cc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMO O15229 6/20 1.00
TRPV4 Q9HBA0 1/20 0.44
STAT3 P40763 1/20 0.44
HTR6 P50406 1/20 0.44
TP53 P04637 1/20 0.43
POLB P06746 1/20 0.42
MYD88 Q99836 1/20 0.42
PLAU P00749 1/20 0.42
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL424366 1.00 KMO (1.00) KMOTRPV4STAT3HTR6TP53
SCHEMBL422729 0.99 KMO (0.98) KMOTRPV4STAT3HTR6TP53
SCHEMBL425012 0.93 KMO (0.87) KMOSTAT3HTR6POLBMYD88
SCHEMBL428975 0.93 KMO (0.87) KMOSTAT3HTR6POLBMYD88
SCHEMBL425616 0.92 KMO (0.85) KMOSTAT3HTR6POLBMYD88
SCHEMBL429355 0.86 KMO (1.00) KMOSTAT3POLBPLAUALDH1A1
SCHEMBL10148194 0.86 KMO (0.84) KMOSTAT3HTR6POLBPLAU
SCHEMBL17146455 0.85 KMO (0.82) KMOSTAT3POLBPLAUALDH1A1
SCHEMBL10148119 0.85 KMO (0.74) KMOTRPV4ALDH1A1MEN1MAPT
SCHEMBL424487 0.84 KMO (0.81) KMOSTAT3POLBPLAUALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118105414-A Application of lactobacillus gasseri JM6 in preparation of products for preventing or treating endometritis 善恩康生物科技(苏州)有限公司 2024-05-31 CN claimed
CN-116789722-A Preparation method of gamithromycin degradation impurity 浙江国邦药业有限公司 2023-09-22 CN claimed
US-12616747-B2 Stabilized beta-coronavirus antigens BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-05-05 US disclosed
US-12617820-B2 Engineered coronavirus spike (s) protein and methods of use thereof BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-05-05 US disclosed
US-20250257102-A1 PREFUSION-STABILIZED HMPV F PROTEINS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-08-14 US disclosed
US-12304930-B2 Prefusion-stabilized hMPV F proteins BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-05-20 US disclosed
CN-119838627-A High-activity in-situ crystallization catalyst and preparation method and application thereof 潍坊正轩稀土催化材料有限公司 2025-04-18 CN disclosed
CN-114553189-B Parallel equalization method based on FPGA 杭州电子科技大学 2025-04-15 CN disclosed
CN-119819353-A High-stability in-situ crystallization catalyst and preparation method and application thereof 潍坊正轩稀土催化材料有限公司 2025-04-15 CN disclosed
CN-119060050-A Benzimidazole compound and application thereof 中国药科大学 2024-12-03 CN disclosed
US-20240376158-A1 PREFUSION-STABILIZED HMPV F PROTEINS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-11-14 US disclosed
US-20230251973-A1 FPGA-Based Parallel Equalization Method HDU FUYANG ELECTRONIC INFORMATION RESEARCH INSTITUTE CO., LTD (CN) 2023-08-10 US disclosed
US-20230242594-A1 ENGINEERED CORONAVIRUS SPIKE (S) PROTEIN AND METHODS OF USE THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-08-03 US disclosed
US-11559565-B2 Methods for treating inflammatory disorders and traumatic brain injury using stabilized non-hematopoietic EPO short peptides UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) 2023-01-24 US disclosed
CN-111880295-B Variable magnification optical system and optical apparatus 株式会社尼康 2022-12-09 CN disclosed
CN-114878703-A Method for determining substance related to gamithromycin 浙江国邦药业有限公司 2022-08-09 CN disclosed
CN-114561307-A Yeast strain culture method with quorum sensing inhibition activity 石河子大学 2022-05-31 CN disclosed
CN-114553189-A Parallel equalization method based on FPGA 杭州电子科技大学富阳电子信息研究院有限公司 2022-05-27 CN disclosed
US-20220153715-A1 PURIFIED 2,5-FURANDICARBOXYLIC ACID PATHWAY PRODUCTS STORA ENSO OYJ (FI) 2022-05-19 US disclosed
CN-112745083-B Barite weight-balance concrete and preparation method thereof 青岛滨海建设天派砼业有限公司 2022-05-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153715-A1 PURIFIED 2,5-FURANDICARBOXYLIC ACID PATHWAY PRODUCTS FDPS, HPD, FLAD1 KMO 161/4885TRPV4 3462/4885STAT3 4649/4885
US-12616747-B2 Stabilized beta-coronavirus antigens LY96, YWHAZ, SARS1 KMO 4878/4885TRPV4 3122/4885STAT3 3155/4885
US-12617820-B2 Engineered coronavirus spike (s) protein and methods of use thereof S100A8, S100A6, Q6ZSR9 KMO 4865/4885TRPV4 3718/4885STAT3 3216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.