Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657283 | 0.73 | MEN1 (0.33) | MEN1KMT2ATSHRTDP1CYP1A2 | |
| SCHEMBL30897428 | 0.68 | GAA (0.32) | ESR1ESR2MAPT | |
| SCHEMBL13379629 | 0.68 | CHRM2 (0.49) | GPR55MEN1LMNAKMT2AESR1 | |
| SCHEMBL13425231 | 0.67 | KDM4E (0.33) | KMT2ACYP1A2 | |
| SCHEMBL2514319 | 0.66 | — | — | |
| SCHEMBL9518749 | 0.66 | KIF11 (0.35) | LMNAALDH1A1TDP1 | |
| SCHEMBL5701610 | 0.65 | KDM4E (0.36) | MAPT | |
| SCHEMBL556904 | 0.65 | KDM4E (0.36) | MAPT | |
| SCHEMBL8817458 | 0.65 | KDM4E (0.37) | — | |
| SCHEMBL13994644 | 0.65 | MMP2 (0.43) | GPR55MEN1LMNAKMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437008-B | Synthesis method of (R) -3-phenyl-3-hydroxymethyl-2, 3-dihydrobenzofuran compound | 常州大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-114437008-A | Synthesis method of (R) -3-phenyl-3-hydroxymethyl-2, 3-dihydrobenzofuran compound | 常州大学 | 2022-05-06 | — | — | CN | disclosed |