Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28431200 | 0.82 | KIF11 (0.37) | KIF11ALDH1A1THRBTDP1LMNA | |
| SCHEMBL9155004 | 0.76 | THRB (0.37) | KIF11ALDH1A1HTTNPSR1THRB | |
| Hydrochloric Acid SCHEMBL28933194 | 0.75 | THRB (0.36) | KIF11ALDH1A1HTTNPSR1THRB | |
| SCHEMBL461337 | 0.75 | THRB (0.40) | KIF11ALDH1A1HTTNPSR1THRB | |
| SCHEMBL4346969 | 0.73 | THRB (0.35) | KIF11THRBTDP1AKR1C1HDAC4 | |
| SCHEMBL9899733 | 0.73 | THRB (0.35) | KIF11NPSR1THRBTDP1AKR1C1 | |
| SCHEMBL9302017 | 0.73 | THRB (0.35) | KIF11ALDH1A1THRBTDP1AKR1C1 | |
| SCHEMBL8491987 | 0.73 | TDP1 (0.35) | KIF11ALDH1A1THRBTDP1AKR1C1 | |
| SCHEMBL8489491 | 0.73 | THRB (0.35) | KIF11THRBTDP1AKR1C1HDAC4 | |
| SCHEMBL28038790 | 0.72 | GAA (0.32) | KIF11AKR1C1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5163198-A | — | — | None | — | — | JP | disclosed |
| JP-H05163198-A | PRODUCTION PROCESS FOR 1,4-NAPHTHALENE-DICARBOXYLIC ACID OR 1-HYDROXYMETHYL-4-NAPHTHOIC ACID | COSMO SOGO KENKYUSHO:KK | 1993-06-29 | — | — | JP | disclosed |