SCHEMBL29639347

SCHEMBL29639347

NC(=S)Nc1ccccc1F

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.59
ALDH1A1 P00352 5/20 0.58
RAB9A P51151 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
NPC1 O15118 1/20 0.57
KDM4E B2RXH2 2/20 0.53
NPSR1 Q6W5P4 1/20 0.53
ALOX12 P18054 1/20 0.53
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
MAPT P10636 2/20 0.51
HPGD P15428 2/20 0.51
LMNA P02545 1/20 0.51
TP53 P04637 1/20 0.50
TYR P14679 1/20 0.50
TSHR P16473 1/20 0.50
TAS2R38 P59533 1/20 0.50
HSD17B10 Q99714 1/20 0.50
GAA P10253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL147200 1.00 L3MBTL1 (0.59) L3MBTL1ALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL9311245 0.84 L3MBTL1 (0.52) L3MBTL1ALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL7593748 0.84 L3MBTL1 (0.71) L3MBTL1ALDH1A1SMN1; SMN2KDM4EALOX12
SCHEMBL5464387 0.83 L3MBTL1 (0.50) L3MBTL1ALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL29838495 0.83 L3MBTL1 (0.50) L3MBTL1ALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL29838503 0.82 ALDH1A1 (0.70) L3MBTL1ALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL5449341 0.82 ALDH1A1 (0.70) L3MBTL1ALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL11162760 0.81 L3MBTL1 (0.49) L3MBTL1ALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL31389917 0.80 L3MBTL1 (0.56) L3MBTL1ALDH1A1RAB9ASMN1; SMN2KDM4E
SCHEMBL790145 0.80 L3MBTL1 (0.47) L3MBTL1ALDH1A1SMN1; SMN2KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118725179-A High-impact fluorine modified polymethyl methacrylate and preparation method and application thereof 中国石油化工股份有限公司 2024-10-01 CN claimed
CN-114432901-B Composite membrane with acid resistance and alkali resistance as well as preparation method and application thereof 中国石油化工股份有限公司 2023-04-11 CN claimed
CN-114432901-A Composite membrane with acid resistance and alkali resistance as well as preparation method and application thereof 中国石油化工股份有限公司 2022-05-06 CN claimed
CN-118725179-A High-impact fluorine modified polymethyl methacrylate and preparation method and application thereof 中国石油化工股份有限公司 2024-10-01 CN disclosed
CN-118619952-A Aloperine derivative, preparation method, pharmaceutical composition and application thereof 中国医学科学院药物研究所 2024-09-10 CN disclosed
CN-114249702-B N-aryl- [2,4 '-dithiazole ] -2' -amine compound and preparation and application thereof 沈阳药科大学 2023-09-05 CN disclosed
CN-114432901-B Composite membrane with acid resistance and alkali resistance as well as preparation method and application thereof 中国石油化工股份有限公司 2023-04-11 CN disclosed
CN-114432901-A Composite membrane with acid resistance and alkali resistance as well as preparation method and application thereof 中国石油化工股份有限公司 2022-05-06 CN disclosed
CN-114249702-A N-aryl- [2,4 '-bithiazole ] -2' -amine compound and preparation and application thereof 沈阳药科大学 2022-03-29 CN disclosed