Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20560678 | 0.83 | CXCR2 (0.40) | ALDH1A1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL4304864 | 0.81 | RAB9A (0.50) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL5464387 | 0.81 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL29838495 | 0.81 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL650892 | 0.81 | MEN1 (0.56) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL29639347 | 0.80 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL147200 | 0.80 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL18550663 | 0.78 | ALDH1A1 (0.61) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL31389917 | 0.78 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6833525 | 0.78 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037351-A1 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037351-A1 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037349-A2 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037349-A2 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |