Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 4/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002678 | 0.81 | KCNH2 (0.43) | KCNH2NOTUMCHRM4CHRM1 | |
| SCHEMBL1993910 | 0.78 | KCNH2 (0.36) | KCNH2AKT1 | |
| SCHEMBL6463345 | 0.77 | ALDH1A1 (0.41) | AKT1ALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL6215597 | 0.74 | KCNH2 (0.53) | KCNH2AKT1NOTUMALDH1A1HPGD | |
| SCHEMBL29640074 | 0.72 | CYP11B2 (0.34) | KCNH2CYP11B2LTA4HALDH1A1HPGD | |
| SCHEMBL1572534 | 0.68 | NOTUM (0.63) | AKT1ROCK2ROCK1NOTUM | |
| SCHEMBL31078186 | 0.68 | NOTUM (0.41) | KCNH2CYP11B2NOTUMLTA4H | |
| SCHEMBL30232786 | 0.68 | NOTUM (0.63) | AKT1ROCK2ROCK1NOTUM | |
| SCHEMBL29640071 | 0.68 | CYP11B2 (0.37) | KCNH2CYP11B2LTA4H | |
| SCHEMBL655024 | 0.67 | NOTUM (0.80) | AKT1ROCK2ROCK1NOTUMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450271-B | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-114450271-A | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2022-05-06 | — | — | CN | disclosed |