Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.67 |
| ▸ | KLK7 | P49862 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.67 |
| ▸ | MEN1 | O00255 | 8/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | TP53 | P04637 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.67 |
| ▸ | MAOA | P21397 | 4/20 | 0.67 |
| ▸ | MAOB | P27338 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.67 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.67 |
| ▸ | XDH | P47989 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28172130 | 1.00 | RAB9A (0.67) | RAB9AKLK7MAPTSMN1; SMN2MEN1 | |
| SCHEMBL29068825 | 0.91 | MAPT (0.80) | RAB9AKLK7MAPTSMN1; SMN2MEN1 | |
| SCHEMBL571576 | 0.88 | XDH (0.84) | RAB9AKLK7MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11942187 | 0.86 | RAB9A (0.59) | RAB9AKLK7MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11937232 | 0.86 | RAB9A (0.59) | RAB9AKLK7MAPTSMN1; SMN2MEN1 | |
| SCHEMBL7030328 | 0.85 | RAB9A (0.81) | RAB9AKLK7MAPTSMN1; SMN2MEN1 | |
| SCHEMBL30573375 | 0.85 | RAB9A (0.81) | RAB9AKLK7MAPTSMN1; SMN2MEN1 | |
| SCHEMBL73754 | 0.85 | ALDH1A1 (0.70) | RAB9AKLK7MAPTSMN1; SMN2MEN1 | |
| Formonetin SCHEMBL4728656 | 0.84 | RAB9A (0.83) | RAB9AKLK7MAPTSMN1; SMN2MEN1 | |
| SCHEMBL5814089 | 0.81 | XDH (0.78) | RAB9AKLK7MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114636764-B | Screening method of anti-inflammatory and antiviral active ingredients of andrographis paniculata | 中国科学院武汉植物园 | 2024-01-26 | — | — | CN | claimed |
| CN-114636764-A | Method for screening anti-inflammatory and antiviral active ingredients of andrographis paniculata | 中国科学院武汉植物园 | 2022-06-17 | — | — | CN | claimed |
| CN-114636764-B | Screening method of anti-inflammatory and antiviral active ingredients of andrographis paniculata | 中国科学院武汉植物园 | 2024-01-26 | — | — | CN | disclosed |
| CN-114636764-A | Method for screening anti-inflammatory and antiviral active ingredients of andrographis paniculata | 中国科学院武汉植物园 | 2022-06-17 | — | — | CN | disclosed |