Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.70 |
| ▸ | RAB9A | P51151 | 8/20 | 0.70 |
| ▸ | MAPT | P10636 | 7/20 | 0.70 |
| ▸ | MEN1 | O00255 | 7/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.70 |
| ▸ | NPC1 | O15118 | 7/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | TP53 | P04637 | 4/20 | 0.70 |
| ▸ | HPGD | P15428 | 3/20 | 0.70 |
| ▸ | MAOB | P27338 | 5/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.67 |
| ▸ | MAOA | P21397 | 2/20 | 0.67 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.67 |
| ▸ | BCL2 | P10415 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11730519 | 0.87 | PIN1 (0.67) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| Formononetin SCHEMBL247496 | 0.87 | KDM4E (0.84) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL7499018 | 0.86 | PIN1 (0.65) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| Isoflavone SCHEMBL4347720 | 0.85 | MAOB (0.63) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL571576 | 0.85 | XDH (0.84) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL28172130 | 0.85 | RAB9A (0.67) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL29640433 | 0.85 | RAB9A (0.67) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL3494129 | 0.84 | MAPT (0.73) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL13640726 | 0.83 | MIF (0.61) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL762092 | 0.82 | MAPT (1.00) | ALDH1A1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903571-A | Isoflavone compound or pharmaceutically acceptable ester or pharmaceutically salt thereof, preparation method and application thereof in preparing medicines for treating pain in vivo and medicines for reducing blood glucose | 郑州大学第一附属医院 | 2023-10-20 | — | — | CN | claimed |
| CN-119060026-A | Benzyl piperidine-containing formononetin derivative and preparation method and application thereof | 贵州大学 | 2024-12-03 | — | — | CN | disclosed |
| CN-116903571-A | Isoflavone compound or pharmaceutically acceptable ester or pharmaceutically salt thereof, preparation method and application thereof in preparing medicines for treating pain in vivo and medicines for reducing blood glucose | 郑州大学第一附属医院 | 2023-10-20 | — | — | CN | disclosed |
| CN-115322168-A | Calycosin derivative and preparation method and application thereof | 桂林医学院 | 2022-11-11 | — | — | CN | disclosed |
| US-8809627-B2 | Plant isoflavone and isoflavanone O-methyltransferase genes | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-8742141-B2 | Inhibition and treatment of prostate cancer metastasis | NORTHWESTERN UNIVERSITY (US) | 2014-06-03 | — | — | US | disclosed |
| US-8742141-B2 | Inhibition and treatment of prostate cancer metastasis | NORTHWESTERN UNIVERSITY (US) | 2014-06-03 | — | — | US | disclosed |
| US-20130296582-A1 | INHIBITION AND TREATMENT OF PROSTATE CANCER METASTASIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-11-07 | — | — | US | disclosed |
| US-20130296582-A1 | INHIBITION AND TREATMENT OF PROSTATE CANCER METASTASIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-11-07 | — | — | US | disclosed |
| US-8481760-B2 | Inhibition and treatment of prostate cancer metastasis | NORTHWESTERN UNIVERSITY (US) | 2013-07-09 | — | — | US | disclosed |
| US-20050172354-A1 | Plant isoflavonoid hydroxylases and methods of use thereof | THE SAMUEL ROBERT NOBLE FOUNDATION | 2005-08-04 | — | — | US | disclosed |
| WO-2005042747-A2 | PLANT ISOFLAVONOID HYDROXYLASES AND METHODS OF USE THEREOF | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2005-05-12 | — | — | WO | disclosed |
| US-20040200139-A1 | Method and composition for tree root colonization | VAMTECH, L.L.C. | 2004-10-14 | — | — | US | disclosed |
| EP-0456808-B1 | METHOD AND COMPOSITIONS FOR STIMULATING VESICULAR-ARBUSCULAR MYCORRHIZAL FUNGI | UNIV MICHIGAN STATE (US) | 1997-10-08 | — | — | EP | disclosed |
| EP-0456808-A4 | METHOD AND COMPOSITIONS FOR STIMULATING VESICULAR-ARBUSCULAR MYCORRHIZAL FUNGI | UNIV MICHIGAN STATE (US) | 1992-11-04 | — | — | EP | disclosed |
| US-5125955-A | Plant safening agents and growth regulators | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 1992-06-30 | — | — | US | disclosed |
| US-5085682-A | Method and compositions for stimulating vesticular-arbuscular mycorrhizal fungi using isoflavonoids | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 1992-02-04 | — | — | US | disclosed |
| EP-0456808-A1 | METHOD AND COMPOSITIONS FOR STIMULATING VESICULAR-ARBUSCULAR MYCORRHIZAL FUNGI. | UNIV MICHIGAN STATE (US) | 1991-11-21 | — | — | EP | disclosed |
| WO-1991007868-A1 | METHOD AND COMPOSITIONS FOR STIMULATING VESICULAR-ARBUSCULAR MYCORRHIZAL FUNGI | MICHIGAN STATE UNIVERSITY (US) | 1991-06-13 | — | — | WO | disclosed |
| US-5002603-A | Stimulating plant growth with isoflavonoid | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 1991-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296582-A1 | INHIBITION AND TREATMENT OF PROSTATE CANCER METASTASIS | MAPK4, MAP4K4, MAP3K4 | ALDH1A1 1204/4885RAB9A 2041/4885MAPT 2493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.