Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.78 |
| ▸ | PARP10 | Q53GL7 | 9/20 | 0.70 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.70 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.70 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 4/20 | 0.70 |
| ▸ | CA9 | Q16790 | 4/20 | 0.70 |
| ▸ | CA12 | O43570 | 3/20 | 0.70 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.70 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.61 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.56 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176891 | 0.88 | CA2 (1.00) | CA2CA1CA9CA12CA14 | |
| SCHEMBL3137816 | 0.84 | PARP10 (1.00) | CA2PARP10PARP15ALDH1A1PARP14 | |
| SCHEMBL2213483 | 0.84 | ALDH1A1 (1.00) | CA2ALDH1A1HTTCA1CA9 | |
| SCHEMBL26416903 | 0.76 | PARP10 (1.00) | CA2PARP10PARP15ALDH1A1PARP14 | |
| SCHEMBL6515525 | 0.76 | SOS1 (1.00) | CA2ALDH1A1HTTCA1CA9 | |
| SCHEMBL6631245 | 0.76 | PARP10 (1.00) | CA2PARP10PARP15ALDH1A1PARP14 | |
| SCHEMBL4856565 | 0.76 | ALDH1A1 (0.83) | CA2ALDH1A1HTTCA1CA9 | |
| SCHEMBL606429 | 0.76 | PARP10 (1.00) | CA2PARP10PARP15ALDH1A1PARP14 | |
| Terephthalamide SCHEMBL4205368 | 0.76 | PARP10 (1.00) | CA2PARP10PARP15ALDH1A1PARP14 | |
| SCHEMBL28256295 | 0.76 | CA2 (0.57) | CA2PARP10PARP15ALDH1A1PARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119189-A | Polypeptides having MMP2 inhibitory effect | 大正制药株式会社 | 2024-12-13 | — | — | CN | disclosed |
| CN-114450294-B | Polypeptides having MMP2 inhibitory effect | 大正制药株式会社 | 2024-11-26 | — | — | CN | disclosed |
| CN-114450294-A | Polypeptide with MMP2 inhibitory effect | 大正制药株式会社 | 2022-05-06 | — | — | CN | disclosed |