Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29640879 | 0.80 | AKR1C3 (0.42) | GAATHRBLMNAKDM4E | |
| SCHEMBL2434546 | 0.79 | EPHX1 (0.33) | SMN1; SMN2GAATHRBTDP1LMNA | |
| SCHEMBL1476384 | 0.75 | L3MBTL1 (0.57) | ESR2ESR1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL18381730 | 0.73 | KMT2A (0.60) | L3MBTL1GAATDP1RECQLKMT2A | |
| SCHEMBL18381729 | 0.73 | KMT2A (0.60) | L3MBTL1GAATDP1RECQLKMT2A | |
| SCHEMBL29425354 | 0.73 | KMT2A (0.60) | L3MBTL1GAATDP1RECQLKMT2A | |
| SCHEMBL174166 | 0.73 | KMT2A (0.60) | L3MBTL1GAATDP1RECQLKMT2A | |
| SCHEMBL28733560 | 0.72 | KMT2A (0.42) | SMN1; SMN2KMT2AP2RX3P2RX2 | |
| SCHEMBL28369254 | 0.72 | ALDH1A1 (0.47) | SMN1; SMN2L3MBTL1GAATHRBKMT2A | |
| SCHEMBL7716645 | 0.71 | ESR1 (0.70) | ESR2ESR1L3MBTL1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218857-B | P300/CBP HAT inhibitors and methods of use thereof | 星座制药公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-114450005-A | Compounds for the treatment of neurological disorders | 星座制药公司 | 2022-05-06 | — | — | CN | disclosed |