Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.51 |
| ▸ | ALB | P02768 | 5/20 | 0.50 |
| ▸ | IL2 | P60568 | 5/20 | 0.50 |
| ▸ | MDM4 | O15151 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.47 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030857 | 1.00 | FOLH1 (0.51) | FOLH1ALBIL2MDM4TP53 | |
| SCHEMBL29398014 | 1.00 | FOLH1 (0.51) | FOLH1ALBIL2MDM4TP53 | |
| SCHEMBL24489613 | 1.00 | FOLH1 (0.51) | FOLH1ALBIL2MDM4TP53 | |
| SCHEMBL14584328 | 1.00 | FOLH1 (0.51) | FOLH1ALBIL2MDM4TP53 | |
| SCHEMBL29500417 | 0.91 | PTPN1 (0.54) | MDM4TP53PTPN1MDM2SLC17A5 | |
| SCHEMBL29843110 | 0.91 | PTPN1 (0.54) | MDM4TP53PTPN1MDM2SLC17A5 | |
| SCHEMBL9732381 | 0.91 | PTPN1 (0.54) | MDM4TP53PTPN1MDM2SLC17A5 | |
| Catechol SCHEMBL18074826 | 0.90 | PTPN1 (0.53) | MDM4TP53PTPN1MDM2SLC17A5 | |
| SCHEMBL120691 | 0.90 | MDM4 (0.52) | MDM4TP53PTPN1MDM2SLC17A5 | |
| SCHEMBL29401272 | 0.90 | MDM4 (0.52) | MDM4TP53PTPN1MDM2SLC17A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4255885-A1 | IODOTYROSINE DERIVATIVES AND PROCESS FOR PREPARING IODOTYROSINE DERIVATIVES | ABX Advanced Biochemical Compounds GmbH (DE) | 2023-10-11 | — | — | EP | disclosed |
| CN-116568694-A | Iodotyrosine derivative and method for preparing iodotyrosine derivative | 爱贝斯高级生化化合物-生物医学研究中心有限公司 | 2023-08-08 | — | — | CN | disclosed |
| EP-4008713-A1 | IODINE TYROSINE DERIVATIVES AND METHOD FOR THE PREPARATION OF IODINE TYROSINE DERIVATIVES | ABX Advanced Biochemical Compounds GmbH (DE) | 2022-06-08 | — | — | EP | disclosed |