SCHEMBL29398014

SCHEMBL29398014

O=C(N[C@H](Cc1ccc(O)c(I)c1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 2/20 0.51
▸ ALB P02768 5/20 0.50
▸ IL2 P60568 5/20 0.50
▸ MDM4 O15151 3/20 0.50
▸ TP53 P04637 3/20 0.50
▸ PTPN1 P18031 2/20 0.50
▸ MDM2 Q00987 2/20 0.47
▸ SLC17A5 Q9NRA2 1/20 0.47
▸ CASP3 P42574 1/20 0.46
▸ EPHX2 P34913 1/20 0.45
▸ TNF P01375 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2030857 1.00 FOLH1 (0.51) FOLH1ALBIL2MDM4TP53
SCHEMBL29641557 1.00 FOLH1 (0.51) FOLH1ALBIL2MDM4TP53
SCHEMBL24489613 1.00 FOLH1 (0.51) FOLH1ALBIL2MDM4TP53
SCHEMBL14584328 1.00 FOLH1 (0.51) FOLH1ALBIL2MDM4TP53
SCHEMBL29500417 0.91 PTPN1 (0.54) MDM4TP53PTPN1MDM2SLC17A5
SCHEMBL29843110 0.91 PTPN1 (0.54) MDM4TP53PTPN1MDM2SLC17A5
SCHEMBL9732381 0.91 PTPN1 (0.54) MDM4TP53PTPN1MDM2SLC17A5
Catechol SCHEMBL18074826 0.90 PTPN1 (0.53) MDM4TP53PTPN1MDM2SLC17A5
SCHEMBL120691 0.90 MDM4 (0.52) MDM4TP53PTPN1MDM2SLC17A5
SCHEMBL29401272 0.90 MDM4 (0.52) MDM4TP53PTPN1MDM2SLC17A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250352678-A1 RADIOPHARMACEUTICALS ADVANCELL IPCO US NO. 1 PTY LTD (AU) 2025-11-20 — — US disclosed
US-20250319213-A1 FUNCTIONALIZED BISAMINOTHIOL DERIVATIVES, COMPLEXES WITH THESE BISAMINOTHIOL DERIVATIVES AND USE OF SAID COMPLEXES AS DIAGNOSTICS AND THERAPEUTICS ABX ADVANCED BIOCHEMICAL COMPOUNDS – BIOMEDIZINISCHE FORSCHUNGSREAGENZIEN GMBH (DE) 2025-10-16 — — US disclosed
US-12419977-B2 Radiopharmaceuticals AdvanCell Isotopes Pty Limited (AU) 2025-09-23 — — US disclosed
EP-4568985-A1 RADIOPHARMACEUTICALS Advancell Isotopes Pty Limited (AU) 2025-06-18 — — EP disclosed
CN-119954773-A PSMA compounds, pharmaceutical compositions comprising the same and uses thereof 苏州威智创科生物有限公司 2025-05-09 — — CN disclosed
WO-2025092841-A1 PSMA COMPOUND, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AND USE THEREOF 山东威智知科药业有限公司 2025-05-08 — — WO disclosed
EP-4529473-A1 FUNCTIONALIZED BISAMINOTHIOL DERIVATIVES, COMPLEXES WITH THESE BISAMINOTHIOL DERIVATIVES AND USE OF SAID COMPLEXES AS DIAGNOSTICS AND THERAPEUTICS ABX Advanced Biochemical Compounds - Biomedizinische Forschungsreagenzien GmbH (DE) 2025-04-02 — — EP disclosed
US-20250064994-A1 RADIOPHARMACEUTICALS ADVANCELL IPCO US NO. 1 PTY LTD (AU) 2025-02-27 — — US disclosed
EP-4464341-A2 PSMA LIGANDS FOR IMAGING AND ENDORADIOTHERAPY Technische Universität München, in Vertretung des Freistaates Bayern (DE) 2024-11-20 — — EP disclosed
EP-4008359-B1 PSMA LIGANDS FOR IMAGING AND ENDORADIOTHERAPY UNIV MUENCHEN TECH (DE) 2024-09-11 — — EP disclosed
EP-4255885-A1 IODOTYROSINE DERIVATIVES AND PROCESS FOR PREPARING IODOTYROSINE DERIVATIVES ABX Advanced Biochemical Compounds GmbH (DE) 2023-10-11 — — EP disclosed
CN-116568694-A Iodotyrosine derivative and method for preparing iodotyrosine derivative 爱贝斯高级生化化合物-生物医学研究中心有限公司 2023-08-08 — — CN disclosed
CN-113354709-B Solid phase synthesis method of metastatic prostate cancer targeting drug precursor 江苏华益科技有限公司 2023-06-09 — — CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
US-11497819-B2 PSMA ligands for imaging and endoradiotherapy Technische Universität München (DE) 2022-11-15 — — US disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
EP-4008713-A1 IODINE TYROSINE DERIVATIVES AND METHOD FOR THE PREPARATION OF IODINE TYROSINE DERIVATIVES ABX Advanced Biochemical Compounds GmbH (DE) 2022-06-08 — — EP disclosed
EP-4008359-A1 PSMA LIGANDS FOR IMAGING AND ENDORADIOTHERAPY Technische Universität München (DE) 2022-06-08 — — EP disclosed
EP-3723815-B1 PSMA LIGANDS FOR IMAGING AND ENDORADIOTHERAPY UNIV MUENCHEN TECH (DE) 2022-04-20 — — EP disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12419977-B2 Radiopharmaceuticals KLK3, FOLH1, PSMA3 FOLH1 2/4885ALB 1675/4885IL2 4788/4885
US-20250319213-A1 FUNCTIONALIZED BISAMINOTHIOL DERIVATIVES, COMPLEXES WITH THESE BISAMINOTHIOL DERIVATIVES AND USE OF SAID COMPLEXES AS DIAGNOSTICS AND THERAPEUTICS MARS1, MARS2, BCAT1 FOLH1 27/4885ALB 524/4885IL2 3068/4885
US-11497819-B2 PSMA ligands for imaging and endoradiotherapy KLK3, FOLH1, EEA1 FOLH1 2/4885ALB 1225/4885IL2 4819/4885
US-20250352678-A1 RADIOPHARMACEUTICALS KLK3, FOLH1, PSMA3 FOLH1 2/4885ALB 1675/4885IL2 4788/4885
US-20250064994-A1 RADIOPHARMACEUTICALS KLK3, FOLH1, PSMA3 FOLH1 2/4885ALB 1675/4885IL2 4788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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