SCHEMBL2030857

SCHEMBL2030857

O=C(N[C@@H](Cc1ccc(O)c(I)c1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 2/20 0.51
▸ ALB P02768 5/20 0.50
▸ IL2 P60568 5/20 0.50
▸ MDM4 O15151 3/20 0.50
▸ TP53 P04637 3/20 0.50
▸ PTPN1 P18031 2/20 0.50
▸ MDM2 Q00987 2/20 0.47
▸ SLC17A5 Q9NRA2 1/20 0.47
▸ CASP3 P42574 1/20 0.46
▸ EPHX2 P34913 1/20 0.45
▸ TNF P01375 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29398014 1.00 FOLH1 (0.51) FOLH1ALBIL2MDM4TP53
SCHEMBL29641557 1.00 FOLH1 (0.51) FOLH1ALBIL2MDM4TP53
SCHEMBL24489613 1.00 FOLH1 (0.51) FOLH1ALBIL2MDM4TP53
SCHEMBL14584328 1.00 FOLH1 (0.51) FOLH1ALBIL2MDM4TP53
SCHEMBL29500417 0.91 PTPN1 (0.54) MDM4TP53PTPN1MDM2SLC17A5
SCHEMBL29843110 0.91 PTPN1 (0.54) MDM4TP53PTPN1MDM2SLC17A5
SCHEMBL9732381 0.91 PTPN1 (0.54) MDM4TP53PTPN1MDM2SLC17A5
Catechol SCHEMBL18074826 0.90 PTPN1 (0.53) MDM4TP53PTPN1MDM2SLC17A5
SCHEMBL120691 0.90 MDM4 (0.52) MDM4TP53PTPN1MDM2SLC17A5
SCHEMBL29401272 0.90 MDM4 (0.52) MDM4TP53PTPN1MDM2SLC17A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12616761-B2 CXCR4-targeting compounds THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2026-05-05 — — US disclosed
US-20260036595-A1 STRUCTURE-BASED PEPTIDES FOR DETECTION OF TRANSTHYRETIN AMYLOID FIBRILS AND AGGREGATES IN PREECLAMPSIA THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-02-05 — — US disclosed
US-20250362310-A1 STRUCTURE-BASED PROBE FOR DETECTION OF TRANSTHYRETIN AMYLOID FIBRILS AND AGGREGATES THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-11-27 — — US disclosed
US-20240342321-A1 NOVEL CXCR4-TARGETING COMPOUNDS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2024-10-17 — — US disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
US-20240100203-A1 NOVEL CXCR4-TARGETING COMPOUNDS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2024-03-28 — — US disclosed
US-20240067599-A1 IODOTYROSINE DERIVATIVES AND PROCESS FOR PREPARING IODOTYROSINE DERIVATIVES ABX ADVANCED BIOCHEMICAL COMPOUNDS - BIOMEDIZINISCHE FORSCHUNGSREAGENZIEN GMBH (DE) 2024-02-29 — — US disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
US-20230391838-A1 Conformationally-Constrained Alpha-RGIA Analogues UNIVERSITY OF UTAH RESEARCH FOUNDATION 2023-12-07 — — US disclosed
EP-4255885-A1 IODOTYROSINE DERIVATIVES AND PROCESS FOR PREPARING IODOTYROSINE DERIVATIVES ABX Advanced Biochemical Compounds GmbH (DE) 2023-10-11 — — EP disclosed
US-20110243845-A1 SOMATOSTATIN ANALOGS WITH INHIBITORY ACTIVITY TO GROWTH HORMONE RELEASE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-10-06 — — US disclosed
US-7968080-B2 Somatostatin analogs with inhibitory activity to growth hormone release THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-06-28 — — US disclosed
US-7968080-B2 Somatostatin analogs with inhibitory activity to growth hormone release THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-06-28 — — US disclosed
US-7968080-B2 Somatostatin analogs with inhibitory activity to growth hormone release THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-06-28 — — US disclosed
CN-100475271-C Somatostatin analogs with inhibitory activity to growth hormone release UNIV CALIFORNIA (US) 2009-04-08 — — CN disclosed
US-20070041902-A1 Somatostatin analogs with inhibitory activity to growth hormone release NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-02-22 — — US disclosed
US-20070041902-A1 Somatostatin analogs with inhibitory activity to growth hormone release NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-02-22 — — US disclosed
CN-1852742-A Somatostatin analogs with inhibitory activity to growth hormone release UNIV CALIFORNIA (US) 2006-10-25 — — CN disclosed
WO-2005018682-A2 SOMATOSTATIN ANALOGS WITH INHIBITORY ACTIVITY TO GROWTH HORMONE RELEASE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-03-03 — — WO disclosed
US-20040014676-A1 SRC kinase inhibitors useful for treating osteoporosis ARIAD PHARMACEUTICALS INC. 2004-01-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240100203-A1 NOVEL CXCR4-TARGETING COMPOUNDS CXCR4, CXCL12, CXCR2 FOLH1 628/4885ALB 4454/4885IL2 3457/4885
US-20240342321-A1 NOVEL CXCR4-TARGETING COMPOUNDS CXCR4, CXCL12, CXCR2 FOLH1 628/4885ALB 4454/4885IL2 3457/4885
US-20070041902-A1 Somatostatin analogs with inhibitory activity to growth hormone release GHRHR, GHSR, SSTR4 FOLH1 135/4885ALB 1376/4885IL2 2094/4885
US-20240067599-A1 IODOTYROSINE DERIVATIVES AND PROCESS FOR PREPARING IODOTYROSINE DERIVATIVES ALK, ALKBH3, INSR FOLH1 4150/4885ALB 1640/4885IL2 4422/4885
US-12616761-B2 CXCR4-targeting compounds CXCR4, CXCR2, CXCR3 FOLH1 756/4885ALB 3504/4885IL2 2639/4885
US-20040014676-A1 SRC kinase inhibitors useful for treating osteoporosis SRC, CTTN, YES1 FOLH1 4763/4885ALB 4259/4885IL2 4693/4885
US-20110243845-A1 SOMATOSTATIN ANALOGS WITH INHIBITORY ACTIVITY TO GROWTH HORMONE RELEASE GHRHR, GHSR, SSTR4 FOLH1 135/4885ALB 1376/4885IL2 2094/4885
US-20260036595-A1 STRUCTURE-BASED PEPTIDES FOR DETECTION OF TRANSTHYRETIN AMYLOID FIBRILS AND AGGREGATES IN PREECLAMPSIA TTR, APP, SERPINA3 FOLH1 380/4885ALB 76/4885IL2 4149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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