Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | CTSS | P25774 | 3/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | CTSH | P09668 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 5/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | RAMP3 | O60896 | 2/20 | 0.40 |
| ▸ | CALCR | P30988 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29415476 | 0.84 | F2 (0.47) | GRB2CTSLCTSSCTSKCTSH | |
| SCHEMBL31152909 | 0.83 | C5AR1 (0.50) | CTSLCTSSCTSKCTSHF2 | |
| SCHEMBL30853586 | 0.83 | SLC6A2 (0.52) | CTSLCTSSCTSKCTSHLNPEP | |
| SCHEMBL29592537 | 0.83 | SLC6A2 (0.47) | — | |
| SCHEMBL29591934 | 0.83 | GRB2 (0.43) | GRB2CTSLCTSSCTSKCTSH | |
| SCHEMBL29590728 | 0.82 | CAPN1 (0.48) | GRB2LNPEPANPEPDPP3F2 | |
| SCHEMBL29463614 | 0.81 | CAPN1 (0.48) | F2APLNRRAMP3CALCR | |
| SCHEMBL29641566 | 0.81 | OPRM1 (0.43) | F2 | |
| SCHEMBL29589034 | 0.81 | TRHR (0.48) | LNPEPDPP3 | |
| SCHEMBL29591887 | 0.81 | REN (0.47) | LNPEPANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220409709-A1 | LABYRINTHIN-BASED PEPTIDES FOR CANCER IMMUNOTHERAPIES AND USES THEREOF | LABYRX IMMUNOLOGIC THERAPEUTICS USA LTD (US) | 2022-12-29 | — | — | US | disclosed |
| US-20220089719-A1 | CONSTRUCTS TARGETING LABYRINTHIN OR A PORTION THEREOF AND USES THEREOF | LABYRX IMMUNOLOGIC THERAPEUTICS (USA) LIMITED (US) | 2022-03-24 | — | — | US | disclosed |