SCHEMBL29641997

SCHEMBL29641997

O=S(=O)(O)c1cc(Cl)c(F)cc1F

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
CA2 P00918 3/20 0.33
PTGES2 Q9H7Z7 2/20 0.33
CA1 P00915 2/20 0.33
CA9 Q16790 1/20 0.33
TET2 Q6N021 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
SGK1 O00141 4/20 0.32
SOS1 Q07889 2/20 0.32
PTPN22 Q9Y2R2 1/20 0.32
CYP3A4 P08684 1/20 0.31
THRB P10828 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31
RECQL P46063 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CA12 O43570 1/20 0.31
CA7 P43166 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13646656 1.00 ALDH1A1 (0.33) ALDH1A1CA2PTGES2CA1CA9
SCHEMBL3949353 0.87 POLB (0.34) ALDH1A1CA2PTGES2CA1CA9
Anthraquinone SCHEMBL28570281 0.86 PGAM1 (0.46) MEN1KMT2A
SCHEMBL6760303 0.81 SLC1A3 (0.41) ALDH1A1CA2CA1TET2TDP1
SCHEMBL29669013 0.80 TRPV4 (0.41) ALDH1A1CA2PTGES2CA1CA9
SCHEMBL29209821 0.80 SGK1 (0.35) ALDH1A1CA2PTGES2CA1CA9
SCHEMBL320432 0.80 TRPV4 (0.41) ALDH1A1CA2PTGES2CA1CA9
SCHEMBL11166520 0.80 PTGES2 (0.37) ALDH1A1CA2PTGES2CA1CA9
SCHEMBL29669007 0.80 TRPV4 (0.41) ALDH1A1CA2PTGES2CA1CA9
Hydrochloric Acid SCHEMBL27910904 0.79 SLC1A3 (0.40) ALDH1A1CA2CA1TET2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114591204-A Preparation and anti-tumor application of anthraquinone sulfonyl spiro derivative 广西大学 2022-06-07 CN disclosed