Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | STAMBP | O95630 | 1/20 | 0.47 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 10/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 3/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30290260 | 0.77 | PSMD14 (0.53) | PSMD14STAMBPCOPS5KCNH2PARP1 | |
| SCHEMBL31182236 | 0.76 | METAP2 (0.50) | GRM2NR1I2KCNH2PDK2PIK3CD | |
| SCHEMBL29859763 | 0.72 | CLK2 (0.48) | GRM2NR1I2KCNH2PDK2PIM1 | |
| SCHEMBL26424534 | 0.71 | ACHE (0.45) | GRM2NR1I2KCNH2PDK2 | |
| SCHEMBL7451848 | 0.71 | PSMD14 (0.61) | PSMD14STAMBPCOPS5PARP1 | |
| SCHEMBL29743564 | 0.70 | PDK2 (0.46) | PDK2 | |
| SCHEMBL31156545 | 0.70 | L3MBTL1 (0.41) | GRM2NR1I2KCNH2PDK2PIK3R2 | |
| SCHEMBL29688144 | 0.69 | PSMD14 (0.66) | PSMD14STAMBPCOPS5GRM2PARP1 | |
| SCHEMBL19346770 | 0.69 | PSMD14 (0.66) | PSMD14STAMBPCOPS5GRM2PARP1 | |
| SCHEMBL29643192 | 0.68 | PSMD14 (0.53) | PSMD14STAMBPCOPS5PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4255911-A1 | BICYCLIC DERIVATIVES | Elanco Tiergesundheit AG (CH) | 2023-10-11 | — | — | EP | claimed |
| WO-2022117783-A1 | BICYCLIC DERIVATIVES | ELANCO TIERGESUNDHEIT AG (CH) | 2022-06-09 | — | — | WO | claimed |