SCHEMBL8134208

SCHEMBL8134208

CCn1c2ccc(F)cc2c2cc(F)ccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.57
MAPT P10636 2/20 0.57
MAPK1 P28482 2/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
ALDH1A1 P00352 3/20 0.50
HPGD P15428 3/20 0.50
HTT P42858 2/20 0.50
HSD17B10 Q99714 2/20 0.50
MEN1 O00255 1/20 0.50
HBB P68871 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
GAA P10253 1/20 0.50
CRY2 Q49AN0 10/20 0.49
PER2 O15055 9/20 0.49
TSHR P16473 1/20 0.49
RORC P51449 1/20 0.48
CRY1 Q16526 8/20 0.48
MPO P05164 1/20 0.46
PLK1 P53350 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15868578 0.91 MAPT (0.65) KDM4EMAPTMAPK1L3MBTL1ALDH1A1
SCHEMBL29643189 0.91 MAPT (0.65) KDM4EMAPTMAPK1L3MBTL1ALDH1A1
SCHEMBL20631884 0.91 KDM4E (0.50) KDM4EMAPTMAPK1L3MBTL1ALDH1A1
SCHEMBL5797737 0.86 KDM4E (0.54) KDM4EMAPTMAPK1L3MBTL1ALDH1A1
SCHEMBL8143242 0.83 MAPT (0.52) KDM4EMAPTMAPK1L3MBTL1ALDH1A1
SCHEMBL8148630 0.80 MAPT (0.54) KDM4EMAPTMAPK1L3MBTL1ALDH1A1
SCHEMBL23469545 0.79 CRY2 (0.44) KDM4EMAPTMAPK1L3MBTL1ALDH1A1
SCHEMBL20097163 0.79 KDM4E (0.56) KDM4EMAPTMAPK1L3MBTL1ALDH1A1
SCHEMBL15774432 0.78 PTGER4 (0.63) KDM4EMAPTALDH1A1HPGDHTT
SCHEMBL24494684 0.77 TUBB4A (0.55) KDM4EMAPTMAPK1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 US disclosed