Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21885662 | 1.00 | GAA (0.57) | GAAALDH1A1POLBTHRBKDR | |
| SCHEMBL14656670 | 0.81 | ALOX15 (0.42) | GAAALDH1A1POLBTHRBPTGES2 | |
| SCHEMBL15563193 | 0.78 | GAA (0.54) | GAAALDH1A1POLBTHRBKDR | |
| SCHEMBL25975127 | 0.76 | OR51E2 (0.47) | GAAALDH1A1POLBTHRBEPHX2 | |
| SCHEMBL9475099 | 0.75 | POLB (0.65) | GAAALDH1A1POLBTHRBKDR | |
| SCHEMBL15147553 | 0.75 | GAA (0.47) | GAAALDH1A1POLBTHRBKDR | |
| SCHEMBL18226248 | 0.73 | CFTR (0.41) | GAAALDH1A1POLBTHRBEPHX2 | |
| SCHEMBL21885673 | 0.72 | ALDH1A1 (0.58) | GAAALDH1A1POLBTHRBKDR | |
| SCHEMBL25998819 | 0.72 | ALDH1A1 (0.45) | GAAALDH1A1POLBTHRBKDR | |
| SCHEMBL5660190 | 0.72 | THRB (0.61) | GAAALDH1A1POLBTHRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115025086-A | Bicyclic heteroaryl derivatives, their preparation and use | 凯瑞康宁生物工程（武汉）有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-110709386-B | Bicyclic heteroaryl derivatives, their preparation and use | 凯瑞康宁生物工程（武汉）有限公司 | 2022-06-07 | — | — | CN | disclosed |