Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | EPRS1 | P07814 | 2/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | CAT | P04040 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14786070 | 1.00 | CES2 (0.35) | CES2CES1EPRS1FABP3FABP4 | |
| SCHEMBL21123400 | 0.84 | KMT2A (0.38) | FABP4MEN1KMT2ANPC1MAPT | |
| SCHEMBL28815980 | 0.84 | FABP3 (0.40) | EPRS1FABP3FABP4GPR35MEN1 | |
| SCHEMBL18675828 | 0.84 | PKM (0.37) | CES2CES1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6302351 | 0.83 | FABP3 (0.44) | CES2CES1EPRS1FABP3FABP4 | |
| SCHEMBL28792146 | 0.83 | GPR35 (0.38) | EPRS1GPR35MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30673290 | 0.83 | FABP3 (0.44) | CES2CES1EPRS1FABP3FABP4 | |
| SCHEMBL29684453 | 0.83 | GPR35 (0.38) | EPRS1GPR35MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31024688 | 0.79 | LMNA (0.43) | MEN1KMT2ASMN1; SMN2NPC1MAPT | |
| SCHEMBL21621671 | 0.79 | LMNA (0.43) | MEN1KMT2ASMN1; SMN2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997081-A1 | INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS | Escape Bio, Inc. (US) | 2022-05-18 | — | — | EP | disclosed |