Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28739066 | 1.00 | FFAR1 (0.44) | FFAR1GRM5USP2TSHRCYP1A2 | |
| SCHEMBL29644422 | 0.93 | FFAR1 (0.49) | FFAR1GRM5USP2TSHRCYP1A2 | |
| SCHEMBL28739128 | 0.93 | FFAR1 (0.49) | FFAR1GRM5USP2TSHRCYP1A2 | |
| SCHEMBL28739188 | 0.87 | LMNA (0.50) | FFAR1SMN1; SMN2MAPTKMT2AHPGD | |
| SCHEMBL29644486 | 0.87 | LMNA (0.50) | FFAR1SMN1; SMN2MAPTKMT2AHPGD | |
| SCHEMBL29644457 | 0.86 | FFAR1 (0.51) | FFAR1USP2CYP2C9CYP3A4MAPT | |
| SCHEMBL28739082 | 0.86 | FFAR1 (0.51) | FFAR1USP2CYP2C9CYP3A4MAPT | |
| SCHEMBL28739056 | 0.86 | MAPK1 (0.46) | FFAR1TSHRMAPTKMT2AHPGD | |
| SCHEMBL29644412 | 0.86 | MAPK1 (0.46) | FFAR1TSHRMAPTKMT2AHPGD | |
| SCHEMBL29644336 | 0.83 | FFAR1 (0.50) | FFAR1USP2CYP2C9SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114507181-B | Propionic acid compound containing 5-substituted tetrahydroisoquinoline, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-03-26 | — | — | CN | disclosed |
| CN-114507181-A | Propionic acid compound containing 5-substituted tetrahydroisoquinoline, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-05-17 | — | — | CN | disclosed |