Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.62 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.62 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.58 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.58 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.58 |
| ▸ | IL1RN | P18510 | 1/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.56 |
| ▸ | NPY2R | P49146 | 1/20 | 0.56 |
| ▸ | NPY4R | P50391 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716988 | 0.96 | OPRD1 (0.63) | OPRM1OPRD1ERAP1ERAP2LNPEP | |
| SCHEMBL7716986 | 0.96 | OPRD1 (0.63) | OPRM1OPRD1ERAP1ERAP2LNPEP | |
| SCHEMBL29577875 | 0.94 | OPRM1 (0.66) | OPRM1OPRD1ERAP1ERAP2LNPEP | |
| SCHEMBL29430079 | 0.93 | LTA4H (0.58) | OPRM1OPRD1ERAP2 | |
| SCHEMBL30011658 | 0.93 | ERAP1 (0.66) | OPRM1OPRD1ERAP1ERAP2LNPEP | |
| SCHEMBL29577861 | 0.93 | OPRM1 (0.67) | OPRM1OPRD1ERAP1ERAP2LNPEP | |
| SCHEMBL30010730 | 0.93 | ERAP1 (0.66) | OPRM1OPRD1ERAP1ERAP2LNPEP | |
| SCHEMBL29577265 | 0.93 | ERAP1 (0.66) | OPRM1OPRD1ERAP1ERAP2LNPEP | |
| SCHEMBL29577019 | 0.93 | OPRM1 (0.67) | OPRM1OPRD1ERAP1ERAP2LNPEP | |
| SCHEMBL30086856 | 0.93 | ERAP2 (0.62) | OPRM1OPRD1ERAP1ERAP2LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220289846-A1 | ANTIBODIES TO HUMAN PROGRAMMED DEATH RECEPTOR PD-1 | ZYDUS LIFESCIENCES LIMITED (IN) | 2022-09-15 | — | — | US | claimed |
| EP-3997126-A1 | ANTIBODIES TO HUMAN PROGRAMMED DEATH RECEPTOR PD-1 | Cadila Healthcare Limited (IN) | 2022-05-18 | — | — | EP | claimed |
| US-12516121-B2 | Antibodies to human programmed death receptor PD-1 | ZYDUS LIFESCIENCES LIMITED (IN) | 2026-01-06 | — | — | US | disclosed |
| US-20220289846-A1 | ANTIBODIES TO HUMAN PROGRAMMED DEATH RECEPTOR PD-1 | ZYDUS LIFESCIENCES LIMITED (IN) | 2022-09-15 | — | — | US | disclosed |
| EP-3997126-A1 | ANTIBODIES TO HUMAN PROGRAMMED DEATH RECEPTOR PD-1 | Cadila Healthcare Limited (IN) | 2022-05-18 | — | — | EP | disclosed |