SCHEMBL9178342

SCHEMBL9178342

Cc1cccc(C(=O)NS(=O)(=O)c2ccc3ccccc3c2)c1

nearest known ligand 0.77

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 14/20 0.77
BCL2L1 Q07817 1/20 0.63
MCL1 Q07820 1/20 0.63
L3MBTL1 Q9Y468 2/20 0.63
MEN1 O00255 1/20 0.63
NPC1 O15118 1/20 0.63
RAB9A P51151 1/20 0.63
KMT2A Q03164 1/20 0.63
HTT P42858 1/20 0.54
HDAC8 Q9BY41 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18311261 0.87 KAT6A (1.00) KAT6A
SCHEMBL9175525 0.86 KAT6A (0.76) KAT6ABCL2L1MCL1L3MBTL1NPC1
SCHEMBL29644482 0.86 KAT6A (0.73) KAT6ABCL2L1MCL1L3MBTL1MEN1
SCHEMBL9179605 0.84 PTGS2 (0.64) KAT6AMEN1KMT2AHDAC8HDAC6
SCHEMBL9179058 0.84 KAT6A (0.74) KAT6ABCL2L1MCL1L3MBTL1MEN1
SCHEMBL9176194 0.83 KAT6A (0.64) KAT6ABCL2L1MCL1MEN1NPC1
SCHEMBL28684588 0.81 ALKBH2 (0.62) KAT6AL3MBTL1MEN1KMT2AHTT
SCHEMBL8664097 0.80 GPR27 (0.58) KAT6AL3MBTL1MEN1NPC1RAB9A
SCHEMBL20119681 0.78 KCNK3 (0.60) KAT6AL3MBTL1MEN1KMT2AHDAC8
SCHEMBL8912421 0.78 GPR27 (0.56) KAT6AL3MBTL1MEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0542556-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 EP claimed
US-5314859-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-05-24 US claimed
EP-0542556-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-05-19 EP claimed
EP-0503856-A1 Thermosensitive recording material OJI PAPER COMPANY LIMITED (JP) 1992-09-16 EP disclosed