Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL550320 | 0.84 | KMT2A (0.50) | MEN1KMT2AL3MBTL1NPSR1POLB | |
| Iodide SCHEMBL29459706 | 0.83 | KMT2A (0.49) | MEN1KMT2AL3MBTL1NPSR1POLB | |
| SCHEMBL5427925 | 0.83 | ALDH1A1 (0.50) | SMN1; SMN2HPGDNPC1RAB9APOLB | |
| SCHEMBL14612238 | 0.81 | L3MBTL1 (0.40) | SMN1; SMN2MEN1KMT2AHPGDGAA | |
| SCHEMBL5179230 | 0.80 | CTSD (0.57) | SMN1; SMN2HPGDGAAALDH1A1 | |
| SCHEMBL5230905 | 0.78 | HPGD (0.56) | SMN1; SMN2MEN1KMT2AHPGDNPC1 | |
| SCHEMBL2963051 | 0.77 | SMN1; SMN2 (0.36) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5180366 | 0.76 | MAPT (0.54) | MEN1KMT2AL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL550488 | 0.75 | PTPN1 (0.42) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL552006 | 0.75 | NPSR1 (0.38) | SMN1; SMN2MEN1KMT2AHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1698619-B1 | PROCESS FOR PRODUCING 2-HALOGENOBENZAMIDE COMPOUND | NIHON NOHYAKU CO LTD (JP) | 2013-11-20 | — | — | EP | disclosed |
| US-7763750-B2 | Process for producing 2-halogenobenzamide compound | NIHON NOHYAKU CO., LTD. (JP) | 2010-07-27 | — | — | US | disclosed |
| US-20070293701-A1 | Process for Producing 2-Halogenobenzamide Compound | NIHON NOHYAKU CO., LTD. (JP) | 2007-12-20 | — | — | US | disclosed |
| EP-1698619-A1 | PROCESS FOR PRODUCING 2-HALOGENOBENZAMIDE COMPOUND | Nihon Nohyaku Co., Ltd. (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293701-A1 | Process for Producing 2-Halogenobenzamide Compound | TYR, CBR3, TH | SMN1; SMN2 4694/4885MEN1 2120/4885KMT2A 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.